Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo
about
KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancerRNA and diseaseInhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansionPeptide antisense nanoparticles.Antisense oligonucleotide therapies: the promise and the challenges from a toxicologic pathologist's perspective.RNAi-mediated c-Rel silencing leads to apoptosis of B cell tumor cells and suppresses antigenic immune response in vivo.Inhibition of Id proteins by a peptide aptamer induces cell-cycle arrest and apoptosis in ovarian cancer cells.Targeting of drugs and nanoparticles to tumors.Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells.ID1 promotes breast cancer metastasis by S100A9 regulation.WSS25 inhibits growth of xenografted hepatocellular cancer cells in nude mice by disrupting angiogenesis via blocking bone morphogenetic protein (BMP)/Smad/Id1 signalingA new module in neural differentiation control: two microRNAs upregulated by retinoic acid, miR-9 and -103, target the differentiation inhibitor ID2ID family protein expression and regulation in hypoxic pulmonary hypertension.Systematic surface engineering of magnetic nanoworms for in vivo tumor targetingID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities.111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolinRegulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression.Tumor penetrating peptides for improved drug delivery.Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression.Transcriptional response of the murine mammary gland to acute progesterone exposureInduction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation.Overcoming biological barriers to in vivo efficacy of antisense oligonucleotides.Micellar hybrid nanoparticles for simultaneous magnetofluorescent imaging and drug deliverySmart drug delivery nanocarriers with self-assembled DNA nanostructures.Recent in vivo advances in cell-penetrating peptide-assisted drug delivery.In vitro characterization and in vivo ultrasound molecular imaging of nucleolin-targeted microbubbles.Inhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity.Azide-alkyne cycloaddition for universal post-synthetic modifications of nucleic acids and effective synthesis of bioactive nucleic acid conjugates.Targeting the bHLH transcriptional networks by mutated E proteins in experimental glioma.Intracellular delivery of peptide nucleic acid and organic molecules using zeolite-L nanocrystals.The Id-protein family in developmental and cancer-associated pathways.Coordination of Id1 and p53 activation by oxidized LDL regulates endothelial cell proliferation and migration.Synthesis and evaluation of an (18) F-labeled derivative of F3 for targeting surface-expressed nucleolin in cancer and tumor endothelial cells.Peptide-mediated Cell and In Vivo Delivery of Antisense Oligonucleotides and siRNA.Id1 expression in endothelial cells of the colon is required for normal response to injury.Targeting of a Helix-Loop-Helix Transcriptional Regulator by a Short Helical Peptide.A de novo self-assembling peptide hydrogel biosensor with covalently immobilised DNA-recognising motifs.Nanoparticulate delivery system targeted to tumor neovasculature for combined anticancer and antiangiogenesis therapy.
P2860
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P2860
Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@ast
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@en
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@nl
type
label
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@ast
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@en
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@nl
prefLabel
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@ast
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@en
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Peptide-conjugated antisense o ...... nscriptional regulator in vivo
@en
P2093
David B Solit
Jonathan Perk
Katia Manova
Luca Cartegni
Neal Rosen
Paola de Candia
Robert Benezra
Yvette Chin
P2860
P2888
P304
P3181
P356
10.1038/NBT1366
P407
P577
2008-01-01T00:00:00Z