Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo - sprookjes - yvandenbroek - TriplyDB

Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo

Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo

http://www.wikidata.org/entity/Q28263669

about

KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer RNA and disease Inhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansion Peptide antisense nanoparticles.Antisense oligonucleotide therapies: the promise and the challenges from a toxicologic pathologist's perspective.RNAi-mediated c-Rel silencing leads to apoptosis of B cell tumor cells and suppresses antigenic immune response in vivo.Inhibition of Id proteins by a peptide aptamer induces cell-cycle arrest and apoptosis in ovarian cancer cells.Targeting of drugs and nanoparticles to tumors.Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells.ID1 promotes breast cancer metastasis by S100A9 regulation.WSS25 inhibits growth of xenografted hepatocellular cancer cells in nude mice by disrupting angiogenesis via blocking bone morphogenetic protein (BMP)/Smad/Id1 signaling A new module in neural differentiation control: two microRNAs upregulated by retinoic acid, miR-9 and -103, target the differentiation inhibitor ID2 ID family protein expression and regulation in hypoxic pulmonary hypertension.Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities.111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression.Tumor penetrating peptides for improved drug delivery.Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4 Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression.Transcriptional response of the murine mammary gland to acute progesterone exposure Induction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation.Overcoming biological barriers to in vivo efficacy of antisense oligonucleotides.Micellar hybrid nanoparticles for simultaneous magnetofluorescent imaging and drug delivery Smart drug delivery nanocarriers with self-assembled DNA nanostructures.Recent in vivo advances in cell-penetrating peptide-assisted drug delivery.In vitro characterization and in vivo ultrasound molecular imaging of nucleolin-targeted microbubbles.Inhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity.Azide-alkyne cycloaddition for universal post-synthetic modifications of nucleic acids and effective synthesis of bioactive nucleic acid conjugates.Targeting the bHLH transcriptional networks by mutated E proteins in experimental glioma.Intracellular delivery of peptide nucleic acid and organic molecules using zeolite-L nanocrystals.The Id-protein family in developmental and cancer-associated pathways.Coordination of Id1 and p53 activation by oxidized LDL regulates endothelial cell proliferation and migration.Synthesis and evaluation of an (18) F-labeled derivative of F3 for targeting surface-expressed nucleolin in cancer and tumor endothelial cells.Peptide-mediated Cell and In Vivo Delivery of Antisense Oligonucleotides and siRNA.Id1 expression in endothelial cells of the colon is required for normal response to injury.Targeting of a Helix-Loop-Helix Transcriptional Regulator by a Short Helical Peptide.A de novo self-assembling peptide hydrogel biosensor with covalently immobilised DNA-recognising motifs.Nanoparticulate delivery system targeted to tumor neovasculature for combined anticancer and antiangiogenesis therapy.

P2860

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P2860

Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo

http://www.wikidata.org/entity/Q28263669

description

2008 nî lūn-bûn

@nan

2008 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

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2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@ast

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@en

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@nl

type

label

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@ast

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@en

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@nl

prefLabel

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@ast

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@en

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@nl

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P1433

Nature Biotechnology

P1476

Peptide-conjugated antisense o ...... nscriptional regulator in vivo

@en

P2093

David B Solit

http://www.w3.org/2001/XMLSchema#string

Jonathan Perk

http://www.w3.org/2001/XMLSchema#string

Katia Manova

http://www.w3.org/2001/XMLSchema#string

Luca Cartegni

http://www.w3.org/2001/XMLSchema#string

Neal Rosen

http://www.w3.org/2001/XMLSchema#string

Paola de Candia

http://www.w3.org/2001/XMLSchema#string

Robert Benezra

http://www.w3.org/2001/XMLSchema#string

Yvette Chin

http://www.w3.org/2001/XMLSchema#string

P2860

Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin

A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo

Nanocrystal targeting in vivo.

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

Id proteins in development, cell cycle and cancer

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

Id family of helix-loop-helix proteins in cancer

Cancer genes and the pathways they control

Combined transcriptional and translational targeting of EWS/FLI-1 in Ewing's sarcoma

P2888

P304

91-100

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scholarly article

P3181

3685617

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P356

10.1038/NBT1366

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P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

26

http://www.w3.org/2001/XMLSchema#string

P50

Vladimir Ponomarev

P577

2008-01-01T00:00:00Z

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5672843

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P698

18176556

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