Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
about
Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13Trypanosoma cruzi macrophage infectivity potentiator has a rotamase core and a highly exposed alpha-helixSolution structure of the Legionella pneumophila Mip-rapamycin complexNMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35Structure and Activity of the Peptidyl-Prolyl Isomerase Domain from the Histone Chaperone Fpr4 toward Histone H3 Proline IsomerizationCrystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteinsA nuclear FK506-binding protein is a histone chaperone regulating rDNA silencing.Solution structure of FK506 bound to FKBP-12Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complexTargets for cell cycle arrest by the immunosuppressant rapamycin in yeastN-terminal extension changes the folding mechanism of the FK506-binding proteinTacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesisA comparison of experimental and computational methods for mapping the interactions present in the transition state for folding of FKBP12Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolutionCyclosporin A-cyclophilin complex formation. A model based on X-ray and NMR data.Selecting folded proteins from a library of secondary structural elements.Classification of rice (Oryza sativa L. Japonica nipponbare) immunophilins (FKBPs, CYPs) and expression patterns under water stress.Solvent Effects on the Energetics of Prolyl Peptide Bond IsomerizationProtein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scaleImmunophilins: switched on protein binding domains?Peptidyl-prolyl isomerases: a new twist to transcription.Structure-affinity properties of a high-affinity ligand of FKBP12 studied by molecular simulations of a binding intermediateRapamycin inhibits vascular smooth muscle cell migration.The chemistry of signal transduction.Enthalpy of hydrogen bond formation in a protein-ligand binding reactionSirolimus pharmacokinetics in pediatric renal transplant recipients receiving calcineurin inhibitor co-therapy.Inhibitor-induced conformational stabilization and structural alteration of a mip-like peptidyl prolyl cis-trans isomerase and its C-terminal domainMolecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyDWater at biomolecular binding interfaces.Neisseria meningitidis encodes an FK506-inhibitable rotamase.Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.Heat capacity changes and hydrophobic interactions in the binding of FK506 and rapamycin to the FK506 binding proteinAn immunophilin that binds M(r) 90,000 heat shock protein: main structural features of a mammalian p59 proteinEscherichia coli trigger factor is a prolyl isomerase that associates with nascent polypeptide chains.Peptidyl-prolyl isomerases: functionality and potential therapeutic targets in cardiovascular disease.Catalytic and ligand binding properties of the FK506 binding protein FKBP12: effects of the single amino acid substitution of Tyr82 to LeuThe wheat peptidyl prolyl cis-trans-isomerase FKBP77 is heat induced and developmentally regulated.Ensemblator v3: Robust atom-level comparative analyses and classification of protein structure ensembles.Bcl-2 and FKBP12 bind to IP3 and ryanodine receptors at overlapping sites: the complexity of protein-protein interactions for channel regulation.
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P2860
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
description
1991 nî lūn-bûn
@nan
1991 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
name
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@ast
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@en
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@nl
type
label
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@ast
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@en
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@nl
prefLabel
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@ast
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@en
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@nl
P2093
P2860
P3181
P356
P1433
P1476
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
@en
P2093
S L Schreiber
S W Michnick
T J Wandless
P2860
P3181
P356
10.1126/SCIENCE.1709301
P407
P577
1991-05-10T00:00:00Z