Systemic complement activation in age-related macular degeneration - sprookjes - yvandenbroek - TriplyDB

Systemic complement activation in age-related macular degeneration

Systemic complement activation in age-related macular degeneration

http://www.wikidata.org/entity/Q28285925

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CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD Complement in age-related macular degeneration: a focus on function Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes Parainflammation, chronic inflammation, and age-related macular degeneration The complotype: dictating risk for inflammation and infection Complement system activation and endothelial dysfunction in patients with age-related macular degeneration (AMD): possible relationship between AMD and atherosclerosis Inhibiting Alternative Pathway Complement Activation by Targeting the Factor D Exosite An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)Fit for the Eye: Aptamers in Ocular Disorders Estimating the predictive ability of genetic risk models in simulated data based on published results from genome-wide association studies.Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration A novel antibody against human properdin inhibits the alternative complement system and specifically detects properdin from blood samples.Animal models of choroidal and retinal neovascularization.Role of ocular complement factor H in a murine model of choroidal neovascularization.The complement component 5 gene and age-related macular degeneration.The role of CRP and inflammation in the pathogenesis of age-related macular degeneration.Associations of complement factor B and complement component 2 genotypes with subtypes of polypoidal choroidal vasculopathy.Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells.A common complement C3 variant is associated with protection against wet age-related macular degeneration in a Japanese population Systemic human CR2-targeted complement alternative pathway inhibitor ameliorates mouse laser-induced choroidal neovascularization.Complement system in pathogenesis of AMD: dual player in degeneration and protection of retinal tissue.Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis Age-related macular degeneration: genetic and environmental factors of disease Single nucleotide polymorphisms in MCP-1 and its receptor are associated with the risk of age related macular degeneration.Zinc supplementation inhibits complement activation in age-related macular degeneration.A profile of transcriptomic changes in the rd10 mouse model of retinitis pigmentosa.Genetics of age-related macular degeneration: current concepts, future directions.The significance of the complement system for the pathogenesis of age-related macular degeneration - current evidence and translation into clinical application Complement factor B polymorphism 32W protects against age-related macular degeneration.The role of macrophage class a scavenger receptors in a laser-induced murine choroidal neovascularization model.The effect of lutein supplementation on blood plasma levels of complement factor D, C5a and C3d.Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy.Impact of the common genetic associations of age-related macular degeneration upon systemic complement component C3d levels Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration.Complement component C5a promotes expression of IL-22 and IL-17 from human T cells and its implication in age-related macular degeneration.CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye.Complementing apolipoprotein secretion by cultured retinal pigment epithelium.Complement factor D in age-related macular degeneration Complement Factor H Expressed by Retinal Pigment Epithelium Cells Can Suppress Neovascularization of Human Umbilical Vein Endothelial Cells: An in vitro Study.

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P2860

Systemic complement activation in age-related macular degeneration

http://www.wikidata.org/entity/Q28285925

description

2008 nî lūn-bûn

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2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2008 թվականի հուլիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Systemic complement activation in age-related macular degeneration

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Systemic complement activation in age-related macular degeneration

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Systemic complement activation in age-related macular degeneration

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Systemic complement activation in age-related macular degeneration

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Systemic complement activation in age-related macular degeneration

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Systemic complement activation in age-related macular degeneration

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Systemic complement activation in age-related macular degeneration

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Systemic complement activation in age-related macular degeneration

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Systemic complement activation in age-related macular degeneration

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Systemic complement activation in age-related macular degeneration

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Beatrix Pollok-Kopp

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Florian Börncke

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Frank G Holz

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Stefanie Janzer

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Thomas Wienker

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P2860

Drusen complement components C3a and C5a promote choroidal neovascularization

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

Complement factor H polymorphism in age-related macular degeneration

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

Complement factor H variant increases the risk of age-related macular degeneration

The human complement factor H: functional roles, genetic variations and disease associations

Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization

Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach

Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits

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