Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors
about
Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein CrkGrb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptorsPDGFRα in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancerA role for Src in signal relay by the platelet-derived growth factor alpha receptorIdentification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing moleculesThe Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis.Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation.Phosphatase of regenerating liver 3 (PRL3) provokes a tyrosine phosphoproteome to drive prometastatic signal transductionAngiotensin II-induced tyrosine phosphorylation of signal transducers and activators of transcription 1 is regulated by Janus-activated kinase 2 and Fyn kinases and mitogen-activated protein kinase phosphatase 1.Retention of PDGFR-beta function in mice in the absence of phosphatidylinositol 3'-kinase and phospholipase Cgamma signaling pathways.Identification of the receptor-associated signaling enzymes that are required for platelet-derived growth factor-AA-dependent chemotaxis and DNA synthesis.Overactivation of phospholipase C-gamma1 renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis.Angiotensin II-induced association of phospholipase Cgamma1 with the G-protein-coupled AT1 receptor.Platelet-derived growth factor-dependent cellular transformation requires either phospholipase Cgamma or phosphatidylinositol 3 kinase.Platelet-derived growth factor (PDGF)-induced Ca2+ signaling in the CG4 oligodendroglial cell line and in transformed oligodendrocytes expressing the beta-PDGF receptor.Identification of a domain within the carboxyl-terminal region of the beta platelet-derived growth factor (PDGF) receptor that mediates the high transforming activity of PDGF.Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke.The oncogenic FIP1L1-PDGFRα fusion protein displays skewed signaling properties compared to its wild-type PDGFRα counterpart.Sustained platelet-derived growth factor receptor alpha signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-gamma pathway.
P2860
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P2860
Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Demonstration of functionally ...... erived growth factor receptors
@ast
Demonstration of functionally ...... erived growth factor receptors
@en
Demonstration of functionally ...... erived growth factor receptors
@nl
type
label
Demonstration of functionally ...... erived growth factor receptors
@ast
Demonstration of functionally ...... erived growth factor receptors
@en
Demonstration of functionally ...... erived growth factor receptors
@nl
prefLabel
Demonstration of functionally ...... erived growth factor receptors
@ast
Demonstration of functionally ...... erived growth factor receptors
@en
Demonstration of functionally ...... erived growth factor receptors
@nl
P2093
P2860
P356
P1476
Demonstration of functionally ...... erived growth factor receptors
@en
P2093
A Eriksson
C H Heldin
G Carpenter
L Claesson-Welsh
U Engström
P2860
P304
P356
10.1074/JBC.270.13.7773
P407
P577
1995-03-01T00:00:00Z