Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis - sprookjes - yvandenbroek - TriplyDB

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

http://www.wikidata.org/entity/Q28288212

about

Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcription Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies A decade of exploring the cancer epigenome - biological and translational implications Epigenetics of cervical cancer. An overview and therapeutic perspectives Sequence and structural analysis of BTB domain proteins Osteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate Therapies An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity A novel POK family transcription factor, ZBTB5, represses transcription of p21CIP1 gene Epigenetic boundaries of tumour suppressor gene promoters: the CTCF connection and its role in carcinogenesis Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1 Lsh is involved in de novo methylation of DNA Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter Osteosarcomagenesis: modeling cancer initiation in the mouse.ZBTB2, a novel master regulator of the p53 pathway.DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer.DNA methylation in the rectal mucosa is associated with crypt proliferation and fecal short-chain fatty acids.Cis lethal genetic interactions attenuate and alter p53 tumorigenesis.How does SIRT1 affect metabolism, senescence and cancer?Genetic methylation and lymphoid malignancies: biomarkers of tumor progression and targeted therapy.A systematic analysis on DNA methylation and the expression of both mRNA and microRNA in bladder cancer Epigenetic regulation of apoptosis and cell cycle in osteosarcoma A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1.DNA hypermethylation markers of poor outcome in laryngeal cancer.Sorting out functions of sirtuins in cancer Loss of a single Hic1 allele accelerates polyp formation in Apc(Δ716) mice Primary neoplasms of bones in mice: retrospective study and review of literature Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis.Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins POK/ZBTB proteins: an emerging family of proteins that regulate lymphoid development and function CpG island methylation of TMS1/ASC and CASP8 genes in cervical cancer.Signification of Hypermethylated in Cancer 1 (HIC1) as Tumor Suppressor Gene in Tumor Progression.Aberrant gene silencing in tumor progression: implications for control of cancer.Array-based comparative genomic hybridization for genomic-wide screening of DNA copy number alterations in aggressive bone tumors.Sirtuins: critical regulators at the crossroads between cancer and aging.Deciphering HIC1 control pathways to reveal new avenues in cancer therapeutics.HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors Requirement for chromatin-remodeling complex in novel tumor suppressor HIC1-mediated transcriptional repression and growth control.Genomic deletion and promoter methylation status of Hypermethylated in Cancer 1 (HIC1) in mantle cell lymphoma.Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients.

P2860

Q21296795-41CBDDD8-2CE7-4B25-8314-8085AB73F498 Q24304378-3CFB7BBA-A497-41B6-82A1-DC08305EBF2F Q24337920-AA49B600-0689-464A-A7A4-7154BB4FC081 Q24614467-FD73BFC8-E1DD-4A6B-95F5-AEDF0CDBC27F Q24812104-0B66B75B-9B21-4E36-9228-3C0AC12A8C01 Q24812693-362DFA8D-A3FE-435D-AFA0-7D4A00413C62 Q26782646-EAE933E2-0878-4317-8AF0-0194601CD92D Q28117824-46309B92-FF7B-4D5B-9FE9-B9C293DE7325 Q28119188-F55B6AF9-4BCF-4200-A49A-2F2A31B8755F Q28264669-A509E2C3-04DF-4176-9FB4-400E368B10BC Q28283017-13876721-8C62-431F-ACEF-464A21B9D4B4 Q28505283-1B5CC594-6AC6-458B-A213-A4D2D18FFF36 Q28506083-397AB524-75FC-4F7C-B847-BB991065DB1F Q30476415-90D5FB8D-161D-48DB-A6B8-4896DFC60144 Q31814767-E4D587D6-3153-4235-8446-EAAAA6C9B216 Q33517453-6EC87811-29B4-4208-9D8D-426B7041CA98 Q33634174-F489A93A-0358-4045-85E4-8B18A09BA1B8 Q33777648-CC875F9A-5BBF-4702-9943-B92F30BBC3BA Q33802917-66E99796-E550-4C2A-B143-1BF9222306A4 Q33913937-086FD9DF-8C83-4398-A26C-B0775E30E75F Q34091387-D8602AC2-F6B6-4994-AEC6-40854A83D2E0 Q34495498-45835B8D-AED0-4A5D-8A42-21E70306DBCB Q34512240-FC1CFB7F-3DCE-48BD-8210-3E3DF488A160 Q34566703-BDF945E0-9777-4203-A24E-CC03D8A26777 Q34970771-42583CEC-2DB9-4F94-9E2E-2DE3C96B8C5B Q35042805-94F466E3-C8BE-4B3B-8B62-DB661D8443C3 Q35151483-AB4D71EE-C95B-483F-8CA0-3B7A478A322A Q35802231-A363C89D-F9C3-45F8-813A-8F7262F2CB21 Q35880084-BA394BBE-93FF-47DD-9DAE-9699C768A998 Q35906761-AADF40AD-2483-4F9B-811E-E963120F4D38 Q35959023-A1A4115A-B05C-46AF-AE69-24ADC1445EC5 Q36284970-F6175B40-17AB-4DED-AE98-FBB7304A71E4 Q36547766-11886067-E831-4E81-929D-D1C11CEC0944 Q36621377-D552C70A-5729-4BC8-B573-69F06982EC35 Q36908428-4425F6D9-C8A1-4245-8C4C-20E2D94AFAD4 Q36931136-033E77CF-CBFD-41C5-8BF3-EAE939EB69C1 Q37073998-BF6A6D31-CC6B-44CE-B6A6-C05F4BF1320D Q37085986-F12FBB35-45A9-4A79-AD5B-55311F900E85 Q37269010-3116F1AC-2200-4B87-9249-FDE1ED8E4F87 Q37269337-55F8ACF1-2062-41F3-8D98-589491B2DB89

P2860

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

http://www.wikidata.org/entity/Q28288212

description

2004 nî lūn-bûn

@nan

2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@ast

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@en

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@nl

type

label

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@ast

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@en

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@nl

prefLabel

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@ast

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@en

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@nl

P1433

Q28288212-530FCA7A-B163-4638-A610-7F2372D47A36

P1476

Q28288212-CEEB0CF3-835C-4B80-B18A-5FB7A4CEC2D2

P2093

Q28288212-2475F197-5F6D-4262-82BB-A5F574A90576

Q28288212-268921CE-0345-4E19-85FB-70492887EE2C

Q28288212-40783B69-5699-42DF-9457-5AE885F30D2F

Q28288212-93748807-36D8-49BF-9FA0-6AAB88D95200

Q28288212-961AEBC7-10C6-4E20-AC15-98534AF04668

Q28288212-A01A32F3-C745-4978-8B26-B03BADE348BE

Q28288212-A13807B6-5D85-468E-A31D-3441EE1C644A

Q28288212-C81E055F-81DD-41C4-A68E-6C270431B4D9

Q28288212-CCF43513-CC89-4E18-8663-0FD9167B660C

Q28288212-E0F2474F-D952-4579-BDE9-AF4A5F174405

P304

Q28288212-46059B2D-EA69-4D60-9C58-52938C184157

P31

Q28288212-A2736A96-524E-471C-9F45-E6DD47D8C593

P356

Q28288212-68CD4BC7-15DF-4105-991A-117B49EB87C6

P407

Q28288212-18EF3305-D37D-491A-BC5C-62E0A067AB47

P433

Q28288212-12B8C724-BAC5-4AB4-9754-C892CFA8E6F7

P478

Q28288212-C2766BA7-F544-450F-B33A-D5F43C77FD9C

P50

Q28288212-14C90225-BD99-420B-8D6F-2E0AEAEE994D

Q28288212-DD9A1CE2-CA50-4231-B512-27B5D74215F0

Q28288212-F719D45D-D7A4-4787-BF6B-87D0158D1EA0

P577

Q28288212-162AF450-B841-4B19-B04B-E91941BF80C5

P5875

Q28288212-2044FC33-42A2-45D0-B2F1-5EBC8A80D362

P698

Q28288212-92386E98-8D4F-4800-814B-F19DE4318158

P356

J.CCR.2004.08.030

P1433

P1476

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

@en

P2093

Arnold J Levine

http://www.w3.org/2001/XMLSchema#string

Cynthia A Zahnow

http://www.w3.org/2001/XMLSchema#string

Jay S Wunder

http://www.w3.org/2001/XMLSchema#string

Joseph L Mankowski

http://www.w3.org/2001/XMLSchema#string

Judith E Karp

http://www.w3.org/2001/XMLSchema#string

Nalan Gokgoz

http://www.w3.org/2001/XMLSchema#string

Stephen B Baylin

http://www.w3.org/2001/XMLSchema#string

Timothy K Cooper

http://www.w3.org/2001/XMLSchema#string

Wenyong Chen

http://www.w3.org/2001/XMLSchema#string

Zhiquan Zhao

http://www.w3.org/2001/XMLSchema#string

P304

387-98

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.CCR.2004.08.030

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P50

Michael Overholtzer

Irene L Andrulis

P577

2004-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8227606

http://www.w3.org/2001/XMLSchema#string

P698

15488761

http://www.w3.org/2001/XMLSchema#string