about
Innate immune sensing of DNA virusesToll-like receptors in systemic lupus erythematosus: potential targets for therapeutic interventionIntracellular nucleic acid sensors and autoimmunityPhagosomal TLR signaling upon Borrelia burgdorferi infectionTLRs and interferons: a central paradigm in autoimmunityTLR8: the forgotten relative revindicatedGuanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cellsMolecular cloning and functional characterization of murine toll‑like receptor 8Transcriptomic analysis of human norovirus NS1-2 protein highlights a multifunctional role in murine monocytesToll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cellsDosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus.The therapeutic potential of Toll-like receptor 7 stimulation in asthma.Spontaneous activation of RNA-sensing pathways in autoimmune disease.Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protectionPoly-thymidine oligonucleotides mediate activation of murine glial cells primarily through TLR7, not TLR8.Activation of NF-κB via endosomal Toll-like receptor 7 (TLR7) or TLR9 suppresses murine herpesvirus 68 reactivation.Humanized TLR7/8 expression drives proliferative multisystemic histiocytosis in C57BL/6 mice.Placental Toll-like receptor 3 and Toll-like receptor 7/8 activation contributes to preeclampsia in humans and mice.Liver-inherent immune system: its role in blood-stage malaria.Role of Toll-like receptor 13 in innate immune recognition of group B streptococci.1,25-Dihydroxyvitamin D3 suppresses TLR8 expression and TLR8-mediated inflammatory responses in monocytes in vitro and experimental autoimmune encephalomyelitis in vivoProtective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.Suppression of molecular inflammatory pathways by Toll-like receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation.The expression of Toll-like receptor 8 and its relationship with VEGF and Bcl-2 in cervical cancer.TLR7 and TLR9 trigger distinct neuroinflammatory responses in the CNSRoles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus.Resurrection of endogenous retroviruses in antibody-deficient miceB-cell selection and the development of autoantibodies.Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9.Unique contribution of IRF-5-Ikaros axis to the B-cell IgG2a response.Impaired toll-like receptor 8 signaling in multiple sclerosis.Role of nucleic acid-sensing TLRs in diverse autoantibody specificities and anti-nuclear antibody-producing B cells.Toll-like receptor 7 rapidly relaxes human airways.Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytesRNA recognition by human TLR8 can lead to autoimmune inflammation.Genetic variations in Toll-like receptors (TLRs 3/7/8) are associated with systemic lupus erythematosus in a Taiwanese population.TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 miceTLR7 Deficiency Leads to TLR8 Compensative Regulation of Immune Response against JEV in MiceMyeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo.Toll-like receptor driven B cell activation in the induction of systemic autoimmunity.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
TLR8 deficiency leads to autoimmunity in mice
@ast
TLR8 deficiency leads to autoimmunity in mice
@en
TLR8 deficiency leads to autoimmunity in mice
@nl
type
label
TLR8 deficiency leads to autoimmunity in mice
@ast
TLR8 deficiency leads to autoimmunity in mice
@en
TLR8 deficiency leads to autoimmunity in mice
@nl
prefLabel
TLR8 deficiency leads to autoimmunity in mice
@ast
TLR8 deficiency leads to autoimmunity in mice
@en
TLR8 deficiency leads to autoimmunity in mice
@nl
P2093
P2860
P50
P356
P1476
TLR8 deficiency leads to autoimmunity in mice
@en
P2093
David M Valenzuela
George D Yancopoulos
Olivier Demaria
Philippe P Pagni
Richard A Flavell
Stephanie Traub
P2860
P304
P356
10.1172/JCI42081
P407
P577
2010-10-01T00:00:00Z