Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex
about
The WASP and WAVE family proteinsThe origins of phagocytosis and eukaryogenesisInclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeletonSPECs, small binding proteins for Cdc42Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffoldCdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actinMIM-B, a putative metastasis suppressor protein, binds to actin and to protein tyrosine phosphatase deltaErk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASPA Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxisA hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome proteinWASH and the Arp2/3 complex regulate endosome shape and trafficking.Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome proteinSrc kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophilsSorting nexin 33 induces mammalian cell micronucleated phenotype and actin polymerization by interacting with Wiskott-Aldrich syndrome proteinFree Brick1 is a trimeric precursor in the assembly of a functional wave complexRecruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesionHaematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerizationDynamin at actin tails.A WASp-VASP complex regulates actin polymerization at the plasma membrane.Motility determinants in WASP family proteins.The state of the filament.Actin-based motility of intracellular microbial pathogensLoss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice.Involvement of the Arp2/3 complex and Scar2 in Golgi polarity in scratch wound modelsThe Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.Arp2/3 complex is required for actin polymerization during platelet shape changeWiskott-Aldrich syndrome protein regulates podosomes in primary human macrophagesSyndapin isoforms participate in receptor-mediated endocytosis and actin organizationDirect regulation of Arp2/3 complex activity and function by the actin binding protein coroninThe intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosisInteraction of the Wiskott-Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cellsCortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.The Wiskott-Aldrich syndromeActivation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motilityStress fibers are generated by two distinct actin assembly mechanisms in motile cellsPivotal role of VASP in Arp2/3 complex-mediated actin nucleation, actin branch-formation, and Listeria monocytogenes motilityDynamics of the actin cytoskeleton mediates receptor cross talk: An emerging concept in tuning receptor signalingActin nucleators in the nucleus: an emerging themeThe on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration
P2860
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P2860
Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@ast
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@en
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@nl
type
label
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@ast
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@en
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@nl
prefLabel
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@ast
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@en
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@nl
P921
P3181
P1433
P1476
Scar1 and the related Wiskott- ...... ton through the Arp2/3 complex
@en
P2093
L M Machesky
P304
P3181
P356
10.1016/S0960-9822(98)00015-3
P407
P577
1998-12-01T00:00:00Z