Embryonic heart and skin defects in mice lacking plakoglobin - sprookjes - yvandenbroek - TriplyDB

Embryonic heart and skin defects in mice lacking plakoglobin

Embryonic heart and skin defects in mice lacking plakoglobin

http://www.wikidata.org/entity/Q28298980

about

A new perspective on intercalated disc organization: implications for heart disease Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin Many roads lead to a broken heart: the genetics of dilated cardiomyopathy.Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation.Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy Assessment of splice variant-specific functions of desmocollin 1 in the skin The desmosome Defining desmosomal plakophilin-3 interactions The amino-terminal domain of desmoplakin binds to plakoglobin and clusters desmosomal cadherin-plakoglobin complexes Defining the interactions between intermediate filaments and desmosomes Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin Xin proteins and intercalated disc maturation, signaling and diseases Desmosome regulation and signaling in disease Mutations with pathogenic potential in proteins located in or at the composite junctions of the intercalated disk connecting mammalian cardiomyocytes: a reference thesaurus for arrhythmogenic cardiomyopathies and for Naxos and Carvajal diseases Differential interaction of plakoglobin and beta-catenin with the ubiquitin-proteasome system Axin directly interacts with plakoglobin and regulates its stability The Armadillo family protein p0071 is a VE-cadherin- and desmoplakin-binding protein Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling A possible role of catenin dyslocalization in pemphigus vulgaris pathogenesis Cardiomyopathy with alopecia and palmoplantar keratoderma (CAPK) is caused by a JUP mutation Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture Normalization of Naxos plakoglobin levels restores cardiac function in mice Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis Lack of plakoglobin in epidermis leads to keratoderma Mechanisms of disease: molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling Lack of plakoglobin leads to lethal congenital epidermolysis bullosa: a novel clinico-genetic entity Requirement for beta-catenin in anterior-posterior axis formation in mice Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling.Cardiac myocyte remodeling mediated by N-cadherin-dependent mechanosensing.Ultrastructural analysis of development of myocardium in calreticulin-deficient mice Salivary proteomics in bisphosphonate-related osteonecrosis of the jaw.Signaling from the adherens junction.Detection of differentially expressed basal cell proteins by mass spectrometry Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms.Integrating animal models and in vitro tissue models to elucidate the role of desmosomal proteins in diseases.The biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium.A possible role for the WNT-1 pathway in oral carcinogenesis.

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P2860

Embryonic heart and skin defects in mice lacking plakoglobin

http://www.wikidata.org/entity/Q28298980

description

1996 nî lūn-bûn

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1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1996年の論文

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1996年論文

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1996年論文

@zh-hant

1996年論文

@zh-hk

1996年論文

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1996年論文

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1996年论文

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name

Embryonic heart and skin defects in mice lacking plakoglobin

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Embryonic heart and skin defects in mice lacking plakoglobin

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Embryonic heart and skin defects in mice lacking plakoglobin

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type

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Embryonic heart and skin defects in mice lacking plakoglobin

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Embryonic heart and skin defects in mice lacking plakoglobin

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Embryonic heart and skin defects in mice lacking plakoglobin

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Embryonic heart and skin defects in mice lacking plakoglobin

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Embryonic heart and skin defects in mice lacking plakoglobin

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Embryonic heart and skin defects in mice lacking plakoglobin

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Developmental Biology

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Embryonic heart and skin defects in mice lacking plakoglobin

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C Bierkamp

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Junction plakoglobin