Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
about
Raf family kinases: old dogs have learned new tricksRecurrent BRAF mutations in Langerhans cell histiocytosisComplex landscapes of somatic rearrangement in human breast cancer genomes.IDH1 and IDH2 mutations in gliomasTo BRAF or not to BRAF: is that even a question anymore?Modern brain tumor imagingMAPK pathway activation in pilocytic astrocytomaThe molecular biology of WHO grade I astrocytomasWill kinase inhibitors make it as glioblastoma drugs?Pathological and molecular advances in pediatric low-grade astrocytomaTargeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyondRecurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapyBRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibitionA mechanism of gene amplification driven by small DNA fragments.The therapeutic potential of targeting the PI3K pathway in pediatric brain tumorsRaf kinases in cancer-roles and therapeutic opportunitiesRecent advances in the understanding of Langerhans cell histiocytosisPilocytic astrocytoma: a disease with evolving molecular heterogeneityA novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activationBreakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer typesIntracranial cystic lesions: a review.Chimeric Genes in Deletions and Duplications Associated with Intellectual DisabilityScreening genes crucial for pediatric pilocytic astrocytoma using weighted gene coexpression network analysis combined with methylation data analysis.Lack of BRAF-V600E Mutation in Papillary Tumor of the Pineal Region.BRAF V600E-mutated diffuse glioma in an adult patient: a case report and review.The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target.A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma.Adult pilocytic astrocytomas: clinical features and molecular analysisMolecular Testing of Brain Tumor.Glioma diagnostics and biomarkers: an ongoing challenge in the field of medicine and scienceActionable molecular biomarkers in primary brain tumors.Pediatric low-grade gliomas: how modern biology reshapes the clinical field.Kinase fusions are frequent in Spitz tumours and spitzoid melanomas.Development, characterization, and reversal of acquired resistance to the MEK1 inhibitor selumetinib (AZD6244) in an in vivo model of childhood astrocytoma.BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model.BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications.Activated MEK cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivoActivated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation.Childhood brain tumors: epidemiology, current management and future directions.Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
P2860
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P2860
Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@ast
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@en
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@nl
type
label
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@ast
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@en
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@nl
prefLabel
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@ast
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@en
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@nl
P2093
P2860
P3181
P1433
P1476
Tandem duplication producing a ...... rity of pilocytic astrocytomas
@en
P2093
Danita M Pearson
David T W Jones
Koichi Ichimura
L Magnus Bäcklund
Sylvia Kocialkowski
V Peter Collins
P2860
P304
P3181
P356
10.1158/0008-5472.CAN-08-2097
P407
P577
2008-11-01T00:00:00Z