Selective modulation of protein kinase C-theta during T-cell activation
about
Direct interaction in T-cells between thetaPKC and the tyrosine kinase p59fynInhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domainMalt1 ubiquitination triggers NF-kappaB signaling upon T-cell activationDephosphorylation of Carma1 by PP2A negatively regulates T-cell activationA motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1Spatial and temporal regulation of protein kinase D (PKD)Control of T lymphocyte morphology by the GTPase Rho.Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand RecognitionPKC-Theta in Regulatory and Effector T-cell FunctionsThe Role of PKC-θ in CD4+ T Cells and HIV Infection: To the Nucleus and Back AgainThe Novel PKCθ from Benchtop to ClinicEarly Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin NetworkModest Interference with Actin Dynamics in Primary T Cell Activation by Antigen Presenting Cells Preferentially Affects Lamellal SignalingIdentification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)Protein kinase C in the immune system: from signalling to chromatin regulationProtein kinase C-δ negatively regulates T cell receptor-induced NF-κB activation by inhibiting the assembly of CARMA1 signalosomeProtein kinase C mu is negatively regulated by 14-3-3 signal transduction proteinsProtein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosisComplex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cellsDynamics of diacylglycerol kinase zeta translocation in living T-cells. Study of the structural domain requirements for translocation and activityCaspase-3-mediated cleavage of protein kinase C theta in induction of apoptosisDeciphering the pathway from the TCR to NF-kappaBPhosphorylation of the protein kinase C-theta activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-kappaB inductionDeficiency of small GTPase Rac2 affects T cell activationPOLKADOTS are foci of functional interactions in T-Cell receptor-mediated signaling to NF-kappaB.Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulationProtein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cellsA 20-amino acid module of protein kinase C{epsilon} involved in translocation and selective targeting at cell-cell contactsThe protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association.Dopamine D1 receptor-mediated inhibition of NADPH oxidase activity in human kidney cells occurs via protein kinase A-protein kinase C cross talk.Differential downstream functions of protein kinase Ceta and -theta in EL4 mouse thymoma cells.A spatiotemporally coordinated cascade of protein kinase C activation controls isoform-selective translocation.Immunological synapse arrays: patterned protein surfaces that modulate immunological synapse structure formation in T cells.Micropatterning of costimulatory ligands enhances CD4+ T cell function.Spatiotemporal patterning during T cell activation is highly diverse.Regulated movement of CD4 in and out of the immunological synapseEssential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster.A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells.
P2860
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P2860
Selective modulation of protein kinase C-theta during T-cell activation
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Selective modulation of protein kinase C-theta during T-cell activation
@ast
Selective modulation of protein kinase C-theta during T-cell activation
@en
Selective modulation of protein kinase C-theta during T-cell activation
@nl
type
label
Selective modulation of protein kinase C-theta during T-cell activation
@ast
Selective modulation of protein kinase C-theta during T-cell activation
@en
Selective modulation of protein kinase C-theta during T-cell activation
@nl
prefLabel
Selective modulation of protein kinase C-theta during T-cell activation
@ast
Selective modulation of protein kinase C-theta during T-cell activation
@en
Selective modulation of protein kinase C-theta during T-cell activation
@nl
P2093
P356
P1433
P1476
Selective modulation of protein kinase C-theta during T-cell activation
@en
P2093
P2888
P356
10.1038/385083A0
P407
P577
1997-01-02T00:00:00Z
P6179
1003608049