Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
about
Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12Glutathione reaction products with a chemical allergen, methylene-diphenyl diisocyanate, stimulate alternative macrophage activation and eosinophilic airway inflammationSequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivityA functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunitsLocal production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejectionCytokine-Induced Modulation of Colorectal CancerRegulation of IL-10 and IL-12 production and function in macrophages and dendritic cellsRegulation of immune responses by prostaglandin E2IL-23: changing the verdict on IL-12 function in inflammation and autoimmunityToll-like receptor 2 (TLR2)-TLR9 crosstalk dictates IL-12 family cytokine production in microglia.The metallopeptide antibiotic bacitracin inhibits interleukin-12 alphabeta and beta2 secretion.Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profile.Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses.In case of obesity, longevity-related mechanisms lead to anti-inflammation.Trypanosomiasis-induced Th17-like immune responses in carp.IL-12 as a therapeutic target for pharmacological modulation in immune-mediated and inflammatory diseases: regulation of T helper 1/T helper 2 responsesRecombinant herpes simplex virus type 1 (HSV-1) codelivering interleukin-12p35 as a molecular adjuvant enhances the protective immune response against ocular HSV-1 challengeCytokine involvement in immunomodulatory activity affected by Candida albicans mannan.Stimulation of nitric oxide production in macrophages by Babesia bovis.Regulation of CD154-induced interleukin-12 production in synovial fluid macrophages.Interleukin-12 p40 mRNA expression in bovine leukemia virus-infected animals: increase in alymphocytosis but decrease in persistent lymphocytosis.Role of interleukin-12 in primary influenza virus infectionConstruction of a single-chain interleukin-12-expressing retroviral vector and its application in cytokine gene therapy against experimental coccidioidomycosis.Role of endogenous interleukin-18 in resolving wild-type and attenuated Salmonella typhimurium infections.Induction and regulation of Th1-inducing cytokines by bacterial DNA, lipopolysaccharide, and heat-inactivated bacteria.Cationic amino acid transporter 2 enhances innate immunity during Helicobacter pylori infection.Intratumoral injection of Propionibacterium acnes suppresses malignant melanoma by enhancing Th1 immune responses.IL-12 family cytokines: immunological playmakersGeneration of a convalescent model of virulent Francisella tularensis infection for assessment of host requirements for survival of tularemiaRole of CD40 ligation in dendritic cell semimaturationInterleukin-12: an update on its immunological activities, signaling and regulation of gene expressionInterleukin-12p40 modulates human metapneumovirus-induced pulmonary disease in an acute mouse model of infectionAlveolar macrophages contribute to the pathogenesis of human metapneumovirus infection while protecting against respiratory syncytial virus infectionIntravenous delivery of HIV-based lentiviral vectors preferentially transduces F4/80+ and Ly-6C+ cells in spleen, important target cells in autoimmune arthritis.Detrimental effects of albuterol on airway responsiveness requires airway inflammation and is independent of β-receptor affinity in murine models of asthmaRegulation of lipopolysaccharide-induced interleukin-12 production by activation of repressor element GA-12 through hyperactivation of the ERK pathwayDepression Correlates with Increased Plasma Levels of Inflammatory Cytokines and a Dysregulated Oxidant/Antioxidant Balance in HIV-1-Infected Subjects Undergoing Antiretroviral Therapy.Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35IL-12 promotes myeloid-derived suppressor cell recruitment and bacterial persistence during Staphylococcus aureus orthopedic implant infectionFasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide in vitro and in vivo.
P2860
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P2860
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@ast
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@en
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@nl
type
label
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@ast
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@en
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@nl
prefLabel
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@ast
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@en
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@nl
P2093
P3181
P356
P1476
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
@en
P2093
Carvajal D
Familletti PC
Podlaski FJ
Stremlo DL
P304
P3181
P356
10.1002/EJI.1830250133
P407
P577
1995-01-01T00:00:00Z