Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor
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Structural and functional studies on platelet-derived growth factorAdditive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell developmentIsolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epitheliumPlatelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complexUnrestricted somatic stem cells from human umbilical cord blood grow in serum-free medium as spheres.Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis.A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activation.RETRACTED: Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class.Platelet-derived growth factor (PDGF) binding promotes physical association of PDGF receptor with phospholipase CTriplex targeting of human PDGF-B (c-sis, proto-oncogene) promoter specifically inhibits factors binding and PDGF-B transcriptionMolecular signal integration. Interplay between serine, threonine, and tyrosine phosphorylationDecreased level of PDGF-stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matrices.Beta-actin mRNA localization is regulated by signal transduction mechanisms.Membrane-anchored form of v-sis/PDGF-B induces mitogenesis without detectable PDGF receptor autophosphorylation.Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling.Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation.Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathwayActivation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variantsAntibody-induced mitogenicity mediated by a chimeric CD2-c-fms receptorThe carboxy-terminal domains of erbB-2 and epidermal growth factor receptor exert different regulatory effects on intrinsic receptor tyrosine kinase function and transforming activityIdentification of tyrosine 706 in the kinase insert as the major colony-stimulating factor 1 (CSF-1)-stimulated autophosphorylation site in the CSF-1 receptor in a murine macrophage cell line.Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells.Biological and biochemical activities of a chimeric epidermal growth factor-Elk receptor tyrosine kinase.Platelet-derived growth factor: mechanism of action and possible in vivo function.B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis.Bovine papillomavirus E5 protein induces the formation of signal transduction complexes containing dimeric activated platelet-derived growth factor beta receptor and associated signaling proteins.Do specific interactions between transmembrane helices play a part in signalling transduction? Exploration with the insulin receptor.Multiple kinase pathways regulate voltage-dependent Ca2+ influx and migration in oligodendrocyte precursor cells.Dissociation of PDGF receptor tyrosine kinase activity from PDGF-mediated inhibition of gap junctional communication.Tyrphostins inhibit PDGF-induced DNA synthesis and associated early events in smooth muscle cells.Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor.TGF-beta inhibits the platelet-derived growth factor-induced formation of inositol trisphosphate in MG-63 human osteosarcoma cells.Deletion of the kinase insert sequence of the platelet-derived growth factor beta-receptor affects receptor kinase activity and signal transduction.Nucleotide-binding properties of kinase-deficient epidermal-growth-factor-receptor mutants.PDGF and intracellular signaling in the timing of oligodendrocyte differentiation.Platelet-derived growth factor stimulates sodium-dependent Pi transport in osteoblastic cells via phospholipase Cgamma and phosphatidylinositol 3' -kinase.Chemotactic peptides but not macrophage colony stimulating factor effect the synthesis of inositol lipids in macrophages.Vasoconstrictor-induced protein-tyrosine phosphorylation in cultured vascular smooth muscle cells.Expression of platelet-derived growth factor (PDGF) and PDGF receptor genes in the developing rat brain.
P2860
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P2860
Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor
description
1988 nî lūn-bûn
@nan
1988 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Role of tyrosine kinase and me ...... derived growth factor receptor
@ast
Role of tyrosine kinase and me ...... derived growth factor receptor
@en
Role of tyrosine kinase and me ...... derived growth factor receptor
@nl
type
label
Role of tyrosine kinase and me ...... derived growth factor receptor
@ast
Role of tyrosine kinase and me ...... derived growth factor receptor
@en
Role of tyrosine kinase and me ...... derived growth factor receptor
@nl
prefLabel
Role of tyrosine kinase and me ...... derived growth factor receptor
@ast
Role of tyrosine kinase and me ...... derived growth factor receptor
@en
Role of tyrosine kinase and me ...... derived growth factor receptor
@nl
P2093
P2860
P356
P1476
Role of tyrosine kinase and me ...... derived growth factor receptor
@en
P2093
J A Escobedo
L T Williams
P2860
P304
P356
10.1128/MCB.8.12.5126
P407
P577
1988-12-01T00:00:00Z