Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
about
The plant-derived glucocorticoid receptor agonist Endiandrin A acts as co-stimulator of colonic epithelial sodium channels (ENaC) via SGK-1 and MAPKsRegulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophagesAltered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition.Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38.Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kappaB-regulated promotersDissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effectsSpecific activation of the glucocorticoid receptor and modulation of signal transduction pathways in human lens epithelial cellsGlucocorticoids synergize with IL-1beta to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cellsGlucocorticoids: do we know how they work?Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage BiologyEndogenous inhibitor proteins that connect Ser/Thr kinases and phosphatases in cell signaling.MKP-1: a critical phosphatase in the biology of macrophages controlling the switch between proliferation and activationA Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune DiseasesMice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptomeDifferential expression and functional analysis of the tristetraprolin family during early differentiation of 3T3-L1 preadipocytesAlterations in gene expression in T1 alpha null lung: a model of deficient alveolar sac developmentEffects of dexamethasone on Muc5ac mucin production by primary airway goblet cellsDexamethasone modulates ErbB tyrosine kinase expression and signaling through multiple and redundant mechanisms in cultured rat hepatocytesCluster analysis of obesity and asthma phenotypesScientific rationale for the use of alpha-adrenergic agonists and glucocorticoids in the therapy of pediatric stridor.Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatasesMinireview: Glucocorticoids in autoimmunity: unexpected targets and mechanisms.A novel mitogen-activated protein kinase phosphatase-1 and glucocorticoid receptor (GR) interacting protein-1-dependent combinatorial mechanism of gene transrepression by GRGlucocorticoid prevents brain-derived neurotrophic factor-mediated maturation of synaptic function in developing hippocampal neurons through reduction in the activity of mitogen-activated protein kinase.Glucocorticoids induce rapid up-regulation of mitogen-activated protein kinase phosphatase-1 and dephosphorylation of extracellular signal-regulated kinase and impair proliferation in human and mouse osteoblast cell linesAnti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma.Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of osteoblast proliferationDysregulation of p38 and MKP-1 in response to NOD1/TLR4 stimulation in sarcoid bronchoalveolar cells.Corticosteroid-resistant inflammatory signalling in Pseudomonas-infected bronchial cellsVitamin D levels, lung function, and steroid response in adult asthma.Role of glucocorticoid-induced leucine zipper (GILZ) in bone acquisitionDexamethasone inhibits the Nox-dependent ROS production via suppression of MKP-1-dependent MAPK pathways in activated microglia.Dexamethasone restrains ongoing expression of interleukin-23p19 in peripheral blood-derived human macrophages.Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patientsInhibition of p38 MAPK by glucocorticoids via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2.Glucocorticoid-induced leucine zipper (GILZ) antagonizes TNF-α inhibition of mesenchymal stem cell osteogenic differentiation.Identification of NURR1 as a mediator of MIF signaling during chronic arthritis: effects on glucocorticoid-induced MKP1Mitogen-activated protein kinase phosphatase-1 - a potential therapeutic target in metabolic disease.
P2860
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P2860
Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@ast
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@en
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@nl
type
label
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@ast
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@en
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@nl
prefLabel
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@ast
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@en
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@nl
P2093
P2860
P3181
P356
P1433
P1476
Glucocorticoids inhibit MAP ki ...... decreased degradation of MKP-1
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/20.24.7108
P407
P577
2001-12-01T00:00:00Z