Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), a
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BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alphaSelective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathwaysIdentification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial apoptotic pathwayIdentification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.ARK5 is a tumor invasion-associated factor downstream of Akt signalingPIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive elementFunctional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetusesAntiapoptotic Effects of EGb 761Systems-scale analysis reveals pathways involved in cellular response to methamphetamineHypoxia--implications for pharmaceutical developmentsThe Loss of HIF1α Leads to Increased Susceptibility to Cadmium-Chloride-Induced Toxicity in Mouse Embryonic FibroblastsNoise-induced changes in gene expression in the cochleae of mice differing in their susceptibility to noise damageSpinophilin facilitates dephosphorylation of doublecortin by PP1 to mediate microtubule bundling at the axonal wrist.Novel multi-modal strategies to promote brain and spinal cord injury recovery.HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease.Ferroptosis: Death by Lipid Peroxidation.Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons.Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α.Differential effects of HIF-1 inhibition by YC-1 on the overall outcome and blood-brain barrier damage in a rat model of ischemic strokeEvidence for a therapeutic effect of Braintone on ischemic brain damageTranscriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress.Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseasesOxygen-sensitive reset of hypoxia-inducible factor transactivation response: prolyl hydroxylases tune the biological normoxic set pointNitric oxide prevents axonal degeneration by inducing HIF-1-dependent expression of erythropoietin.Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin.Molecular targets of the multifunctional iron-chelating drug, M30, in the brains of mouse models of type 2 diabetes mellitusHistone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathwayCarbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1.Prophylactic neuroprotection against stroke: low-dose, prolonged treatment with deferoxamine or deferasirox establishes prolonged neuroprotection independent of HIF-1 function.Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis.Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibers of MPP+/MPTP-Lesioned Dopaminergic Neurons.Erythropoietin in brain development and beyond.Hypoxic preconditioning protects against ischemic brain injury.Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation.Inhibition of NGF deprivation-induced death by low oxygen involves suppression of BIMEL and activation of HIF-1Metabolism and epigenetics in the nervous system: Creating cellular fitness and resistance to neuronal death in neurological conditions via modulation of oxygen-, iron-, and 2-oxoglutarate-dependent dioxygenases.Lactate dehydrogenase-5 (LDH-5) overexpression in non-small-cell lung cancer tissues is linked to tumour hypoxia, angiogenic factor production and poor prognosis.Hypoxic adaptation engages the CBP/CREST-induced coactivator complex of Creb-HIF-1α in transactivating murine neuroblastic glucose transporter.
P2860
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P2860
Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), a
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Protection from oxidative stre ...... tic enzymes, p21(waf1/cip1), a
@en
Protection from oxidative stre ...... tic enzymes, p21(waf1/cip1), a
@nl
type
label
Protection from oxidative stre ...... tic enzymes, p21(waf1/cip1), a
@en
Protection from oxidative stre ...... tic enzymes, p21(waf1/cip1), a
@nl
prefLabel
Protection from oxidative stre ...... tic enzymes, p21(waf1/cip1), a
@en
Protection from oxidative stre ...... tic enzymes, p21(waf1/cip1), a
@nl
P2093
P3181
P1476
Protection from oxidative stre ...... waf1/cip1), and erythropoietin
@en
P2093
G L Semenza
J C Marquis
J M Baraban
K O'Donovan
M P Miller
P304
P3181
P356
10.1523/JNEUROSCI.19-22-09821.1999
P407
P577
1999-11-01T00:00:00Z