Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation - sprookjes - yvandenbroek - TriplyDB

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

http://www.wikidata.org/entity/Q28378802

about

Short-term calorie restriction in male mice feminizes gene expression and alters key regulators of conserved aging regulatory pathways Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1 DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death Signaling by target of rapamycin proteins in cell growth control Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine-111)A new translational regulator with homology to eukaryotic translation initiation factor 4G Attenuated APC alleles produce functional protein from internal translation initiation.Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation Protein kinases and phosphatases in the control of cell fate Coupling of cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator Pushing the envelope in the mTOR pathway: the second generation of inhibitors The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1 mTOR signaling: at the crossroads of plasticity, memory and disease Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1 Immunosuppressive potency of mechanistic target of rapamycin inhibitors in solid-organ transplantation Effects of TORC1 Inhibition during the Early and Established Phases of Polycystic Kidney Disease Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1 Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication.Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast.TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae.Saccharomyces cerevisiae FKBP12 binds Arabidopsis thaliana TOR and its expression in plants leads to rapamycin susceptibility.Posttranscriptional control of gene expression in yeast.Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae.A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E.Cell wall integrity modulates RHO1 activity via the exchange factor ROM2 mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action Hierarchical phosphorylation of the translation inhibitor 4E-BP1 Integrating signals from T-cell receptor and serum by T cells enhance translation of tumour necrosis factor-alpha Modifications of eukaryotic initiation factor 4F (eIF4F) in adult cardiocytes by adenoviral gene transfer: differential effects on eIF4F activity and total protein synthesis rates Rapamycin stimulates viral protein synthesis and augments the shutoff of host protein synthesis upon picornavirus infection

P2860

Q21091205-8B4851C8-3DA3-443C-AF01-1F47E0B58609 Q22010667-4204F3B1-98EE-4F3A-8E91-B2DEDE26827A Q22254290-C8A1401D-98CB-47AE-A636-852EFADACAC3 Q24310613-FF69C629-2E47-43AB-8498-76B49616BA93 Q24319844-1E70E352-9E0E-411D-A6B4-0F4974EEB8FE Q24522447-69DCAF33-2E98-4354-99DC-FAA766BA6C50 Q24531289-71B70CE8-E0B7-4BA1-B764-AA2F5279F31B Q24532110-CBA71BAC-C284-4A74-8733-CF9F37F55CCC Q24534442-212AFC04-E24F-42DA-86E9-C0C82B017AE0 Q24537557-A1223F7F-2045-475B-B434-ABAD4D47935F Q24554226-E4748E31-4463-4F11-9695-341CB52C2193 Q24600427-3BC10D12-6FA0-437D-9B9D-D24091ABFE09 Q24604987-9F3C8E7E-2414-4137-855B-AA249B8B91FC Q24606696-37EB721A-8FB2-4F05-AC48-3B72505EFD20 Q24609227-C63C319F-E90D-4A59-ADB1-B5EB55271680 Q24622222-90C8490D-7642-4CE1-9CF1-D408BF41234E Q24634783-BE630982-0EEA-4DAA-92B1-7FF06317252C Q24647655-41D6A5E4-5EC4-4A26-BF5D-A99E9A741A63 Q24648355-A8CE546A-B5AE-4544-BBBD-854A9528CC51 Q24682697-920CCC73-8C69-4006-904D-E85D186568AE Q26751433-6698B617-D764-4FBB-BD8B-33F30615A082 Q27320627-39E591C1-AFCB-40F0-B8F3-0D115ECF3438 Q27331645-549756FD-40EE-4B11-9860-DB41CD717533 Q27470019-7DF210E0-410C-4D9F-BAC1-029F5D8A16A4 Q27824772-14E60913-F675-4D1D-A97C-4BF594A1D2F2 Q27930579-96EBE2D4-3683-4403-8A0B-594F0F51EDEB Q27932036-25C33A32-B62E-4C25-9DED-2D69BDCB6369 Q27932207-1557BD48-9EDE-444B-AF18-4C96B301D083 Q27935025-065DC5E1-6D04-4850-AB0A-5273EE0C071F Q27937074-4888D6F7-1638-49B2-89A1-BE1D77AF3318 Q27937080-069B142F-7BCB-4B4D-85BB-63B6E5117E69 Q27938852-509D8B62-F7D2-467A-B76F-BEBF59F3B4B3 Q27940188-C39D8D48-BDEE-4C80-8679-C818574ACA9B Q28081540-BA1DAB71-AAA9-44FF-BBAB-AE112A688E6B Q28343389-88826C6F-85BE-4BFE-BA33-F3B9CF35C731 Q28343624-1D67DB5E-2561-4125-A8F0-BADBE7E3E391 Q28363125-284D5797-61EF-4651-9B17-3381A1035C34 Q28363949-6D8C2722-B834-4F1B-88AD-A28D568C9972 Q28365607-DA8D5205-259D-4C50-93C8-B3249563F2E8 Q28379360-7B36F8F1-B5D6-4974-8982-75166634FB1D

P2860

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

http://www.wikidata.org/entity/Q28378802

description

1996 nî lūn-bûn

@nan

1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

1996年の論文

@ja

1996年論文

@yue

1996年論文

@zh-hant

1996年論文

@zh-hk

1996年論文

@zh-mo

1996年論文

@zh-tw

1996年论文

@wuu

name

Rapamycin blocks the phosphory ...... dent initiation of translation

@ast

Rapamycin blocks the phosphory ...... dent initiation of translation

@en

Rapamycin blocks the phosphory ...... dent initiation of translation

@nl

type

label

Rapamycin blocks the phosphory ...... dent initiation of translation

@ast

Rapamycin blocks the phosphory ...... dent initiation of translation

@en

Rapamycin blocks the phosphory ...... dent initiation of translation

@nl

prefLabel

Rapamycin blocks the phosphory ...... dent initiation of translation

@ast

Rapamycin blocks the phosphory ...... dent initiation of translation

@en

Rapamycin blocks the phosphory ...... dent initiation of translation

@nl

P1433

Q28378802-3CED479B-151A-4350-B79A-9EB9E6358544

P1476

Q28378802-8FCF2FF4-5515-4C85-96E6-191D2AC855AA

P2093

Q28378802-20778B23-BC25-45EA-8534-0633C8BD16FD

Q28378802-3FC92A5F-6CB8-4DA1-BD6F-57D546831FD4

Q28378802-832AC44E-D143-413A-B026-4C73FA237C39

Q28378802-8BEBF118-682D-422E-95A5-F1310B8374C7

Q28378802-C7743133-7656-4969-A60C-5989A27E887E

P2860

Q28378802-01624F72-5787-47D9-82F1-B1F493C88985

Q28378802-06C18F08-B419-4186-9284-58FADFA62CA0

Q28378802-0793997F-57BE-4D0F-9507-F88278918ED5

Q28378802-0B7A9418-0DAA-4C16-8400-EB39F83BE994

Q28378802-0D01A384-DA7B-4C5E-93F5-16FEAD3D0482

Q28378802-1741026E-A607-4006-AEE1-ADB37AE6B3D4

Q28378802-253DB549-56BB-4F41-B6A0-E7981A542E12

Q28378802-2A45754A-CA79-4CC6-A230-22DAA3F7CE97

Q28378802-35E88E5D-7737-4DAA-9D27-C74D028E4FEF

Q28378802-3A754825-ECEF-4E70-9C25-BA6402995170

P304

Q28378802-E4E07438-8FE5-477E-AACF-EE0658F6C187

P31

Q28378802-9FAD9112-DA4F-4112-9A60-3453EC4E6FF4

P3181

Q28378802-32E89E22-CD6C-49C8-A0A7-D86B6C541CC1

P356

Q28378802-841228EB-9A1C-433D-8D24-6B070F4BB2A7

P407

Q28378802-E4F13E25-8E87-4722-B8A4-CA4305DB6679

P433

Q28378802-0813A14B-BB89-4EF7-B416-C67C28C4D59B

P478

Q28378802-D27E6A27-AAF0-4DB2-AD53-E2A29F009206

P577

Q28378802-1399B9D0-1C1D-4216-B6CF-8188EF360421

P698

Q28378802-A2F2A2DB-1990-489E-A80F-2AC414BB8E4D

P921

Q28378802-523FA138-1581-457B-BB2F-D5406E4E2CF8

P932

Q28378802-643C8691-F4A5-4177-9A2F-8520DF93CDEB

P3181

P356

J.1460-2075.1996.TB00398.X

P1433

The EMBO Journal

P1476

Rapamycin blocks the phosphory ...... dent initiation of translation

@en

P2093

A C Gingras

http://www.w3.org/2001/XMLSchema#string

L Beretta

http://www.w3.org/2001/XMLSchema#string

M N Hall

http://www.w3.org/2001/XMLSchema#string

N Sonenberg

http://www.w3.org/2001/XMLSchema#string

Y V Svitkin

http://www.w3.org/2001/XMLSchema#string

P2860

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins

Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

CDC33 encodes mRNA cap-binding protein eIF-4E of Saccharomyces cerevisiae

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes

Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast

P304

658-664

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2770771

http://www.w3.org/2001/XMLSchema#string

P356

10.1002/J.1460-2075.1996.TB00398.X

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

15

http://www.w3.org/2001/XMLSchema#string

P577

1996-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

8599949

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

449984

http://www.w3.org/2001/XMLSchema#string