Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers - sprookjes - yvandenbroek - TriplyDB

Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers

Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers

http://www.wikidata.org/entity/Q28389551

about

Epigenetics of lung cancer Correlation between the methylation of SULF2 and WRN promoter and the irinotecan chemosensitivity in gastric cancer Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers GATA2 is epigenetically repressed in human and mouse lung tumors and is not requisite for survival of KRAS mutant lung cancer.Cigarette smoking and p16INK4α gene promoter hypermethylation in non-small cell lung carcinoma patients: a meta-analysis.Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer.The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.Meta-analyses of gene methylation and smoking behavior in non-small cell lung cancer patients.Ambient PM exposure and DNA methylation in tumor suppressor genes: a cross-sectional study.Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15.Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer Methylated Genes in Sputum Among Older Smokers With Asthma.Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma.Biomarkers and the genetics of early neoplastic lesions.Defining a gene promoter methylation signature in sputum for lung cancer risk assessment.Maternal smoking as a model for environmental epigenetic changes affecting birthweight and fetal programming.A three-gene signature as potential predictive biomarker for irinotecan sensitivity in gastric cancer.Aerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model.Smoking and microRNA dysregulation: a cancerous combination.Increased methylation of lung cancer-associated genes in sputum DNA of former smokers with chronic mucous hypersecretion.CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non-small-cell lung cancer.DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis.Genetic and epigenetic changes in lung carcinoma and their clinical implications.DNA methylation biomarkers in cancer: progress towards clinical implementation.Targeting of cancer stem cells by inhibitors of DNA and histone methylation.MicroRNA-143 is downregulated in breast cancer and regulates DNA methyltransferases 3A in breast cancer cells.Genetic and epigenetic analysis of non-small cell lung cancer with NotI-microarrays.Epigenetic therapy of non-small cell lung cancer using decitabine (5-aza-2'-deoxycytidine).DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung.Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model.Genome-wide DNA methylation assay reveals novel candidate biomarker genes in cervical cancer.Genome-wide CpG island methylation analyses in non-small cell lung cancer patients.Oncogenic Role of BOLL in Colorectal Cancer.Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer.

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Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers

http://www.wikidata.org/entity/Q28389551

description

2009 nî lūn-bûn

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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Concomitant promoter methylati ...... rent, former and never smokers

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Concomitant promoter methylati ...... rent, former and never smokers

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Concomitant promoter methylati ...... rent, former and never smokers

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Concomitant promoter methylati ...... rent, former and never smokers

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Concomitant promoter methylati ...... rent, former and never smokers

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Christine A Stidley

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Emi O Machida

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Kornel E Schuebel

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Mathewos Tessema

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Stephen B Baylin

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Steven A Belinsky

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Yang Y Yu

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P2860

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island

DNA damage, homology-directed repair, and DNA methylation

Two genetic hits (more or less) to cancer

Lung cancer incidence in never smokers

Human BOULE gene rescues meiotic defects in infertile flies

HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer

Somatic mutations affect key pathways in lung adenocarcinoma

Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma

Global cancer statistics, 2002

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