Development of functional genomic tools in trematodes: RNA interference and luciferase reporter gene activity in Fasciola hepatica - sprookjes - yvandenbroek - TriplyDB

Development of functional genomic tools in trematodes: RNA interference and luciferase reporter gene activity in Fasciola hepatica

Development of functional genomic tools in trematodes: RNA interference and luciferase reporter gene activity in Fasciola hepatica

http://www.wikidata.org/entity/Q28473071

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A portrait of the transcriptome of the neglected trematode, Fasciola gigantica--biological and biotechnological implications Unlocking the transcriptomes of two carcinogenic parasites, Clonorchis sinensis and Opisthorchis viverrini The tumorigenic liver fluke Opisthorchis viverrini--multiple pathways to cancer Genetic manipulation of schistosomes--progress with integration competent vectors Stimulating Neoblast-Like Cell Proliferation in Juvenile Fasciola hepatica Supports Growth and Progression towards the Adult Phenotype In Vitro Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivo Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference.Electroporation facilitates introduction of reporter transgenes and virions into schistosome eggs.Survey of transcripts expressed by the invasive juvenile stage of the liver fluke Fasciola hepatica Suppression of aquaporin, a mediator of water channel control in the carcinogenic liver fluke, Opisthorchis viverrini.Genetic manipulation of Schistosoma haematobium, the neglected schistosome.RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro.Molecular characterization of a tetraspanin from the human liver fluke, Opisthorchis viverrini.Culture for genetic manipulation of developmental stages of Schistosoma mansoni Quantitative retrotransposon anchored PCR confirms transduction efficiency of transgenes in adult Schistosoma mansoni Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.Suppression of Ov-grn-1 encoding granulin of Opisthorchis viverrini inhibits proliferation of biliary epithelial cells.Schistosoma mansoni U6 gene promoter-driven short hairpin RNA induces RNA interference in human fibrosarcoma cells and schistosomules.Fasciola hepatica vaccine: we may not be there yet but we're on the right road Transfection of Platyhelminthes.Human U6 promoter drives stronger shRNA activity than its schistosome orthologue in Schistosoma mansoni and human fibrosarcoma cells.Transient transgenesis of the tapeworm Taenia crassiceps.Calmodulin disruption impacts growth and motility in juvenile liver fluke.In vitro manipulation of gene expression in larval Schistosoma: a model for postgenomic approaches in Trematoda.RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini.Progress with schistosome transgenesis RNA interference targeting leucine aminopeptidase blocks hatching of Schistosoma mansoni eggs.Genetics and genomics converge on the human blood fluke.Functional genomics approaches in parasitic helminths.The global burden of fasciolosis in domestic animals with an outlook on the contribution of new approaches for diagnosis and control.Conservation and diversification of small RNA pathways within flatworms.Differential expression and localization of saposin-like protein 2 of Fasciola hepatica.RNA interference in Fasciola gigantica: Establishing and optimization of experimental RNAi in the newly excysted juveniles of the fluke.Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes.Functional characterization of single-domain cystatin-like cysteine proteinase inhibitors expressed by the trematode Fasciola hepatica.Harnessing Genomic Technologies to Explore the Molecular Biology of Liver Flukes-Major Implications for Fundamental and Applied Research

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P2860

Development of functional genomic tools in trematodes: RNA interference and luciferase reporter gene activity in Fasciola hepatica

http://www.wikidata.org/entity/Q28473071

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2008 nî lūn-bûn

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PLOS Neglected Tropical Diseases

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Development of functional geno ...... activity in Fasciola hepatica

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Estela Castillo

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Gabriel Rinaldi

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José F Tort

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Maria E Morales

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Draft genome of the filarial nematode parasite Brugia malayi

Caenorhabditis elegans SID-2 is required for environmental RNA interference

Proteomic analysis of Fasciola hepatica excretory-secretory products.

Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni.

HSP70-controlled GFP expression in transiently transformed schistosomes.

Characterisation of the cysteine protease ER60 in transgenic Schistosoma mansoni larvae.

Biolistic transformation of Schistosoma mansoni with 5' flanking regions of two peptidase genes promotes tissue-specific expression.

The uptake of Texas Red-BSA in the excretory system of schistosomes and its colocalisation with ER60 promoter-induced GFP in transiently transformed adult males.

Potential role of a CD36-like class B scavenger receptor in the binding of modified low-density lipoprotein (acLDL) to the tegumental surface of Schistosoma mansoni sporocysts.

New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum.

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