Myosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formation
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Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseConcerning immune synapses: a spatiotemporal timelineRegulation of T-cell receptor signaling by the actin cytoskeleton and poroelastic cytoplasmCell biological steps and checkpoints in accessing NK cell cytotoxicityCell polarisation and the immunological synapseControversy and consensus regarding myosin II function at the immunological synapseT Lymphocyte Myosin IIA is Required for Maturation of the Immunological SynapseIntegration of the movement of signaling microclusters with cellular motility in immunological synapses.CD28 and CD3 have complementary roles in T-cell traction forces.Cytoskeletal forces during signaling activation in Jurkat T-cells.Nuclear envelope lamin-A couples actin dynamics with immunological synapse architecture and T cell activation.DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity.Actin polymerization-dependent activation of Cas-L promotes immunological synapse stabilitySize-based chromatography of signaling clusters in a living cell membraneSoluble CD27-pool in humans may contribute to T cell activation and tumor immunity.Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathwayThe activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold.DNA-mediated assembly of protein heterodimers on membrane surfaces.Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cellsCalcium influx through CRAC channels controls actin organization and dynamics at the immune synapse.Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activationFormin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse.The role of the cytoskeleton at the immunological synapse.Molecular control of B cell activation and immunological synapse formation.Membrane adhesion and the formation of heterogeneities: biology, biophysics, and biotechnology.Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner.Sustained α-catenin Activation at E-cadherin Junctions in the Absence of Mechanical Force.T cell immunoengineering with advanced biomaterials.Janus particles as artificial antigen-presenting cells for T cell activation.Substrate stiffness governs the initiation of B cell activation by the concerted signaling of PKCβ and focal adhesion kinase.Ratiometric Tension Probes for Mapping Receptor Forces and Clustering at Intermembrane Junctions.High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation.αβ T Cell Receptor Mechanosensing Forces out Serial EngagementThe Actin Cytoskeleton: A Mechanical Intermediate for Signal Integration at the Immunological Synapse
P2860
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P2860
Myosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formation
description
2012 nî lūn-bûn
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2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
Myosin IIA modulates T cell re ...... mmunological synapse formation
@ast
Myosin IIA modulates T cell re ...... mmunological synapse formation
@en
Myosin IIA modulates T cell re ...... mmunological synapse formation
@nl
type
label
Myosin IIA modulates T cell re ...... mmunological synapse formation
@ast
Myosin IIA modulates T cell re ...... mmunological synapse formation
@en
Myosin IIA modulates T cell re ...... mmunological synapse formation
@nl
prefLabel
Myosin IIA modulates T cell re ...... mmunological synapse formation
@ast
Myosin IIA modulates T cell re ...... mmunological synapse formation
@en
Myosin IIA modulates T cell re ...... mmunological synapse formation
@nl
P2093
P2860
P50
P3181
P1433
P1476
Myosin IIA modulates T cell re ...... mmunological synapse formation
@en
P2093
Alexander A Smoligovets
Jay T Groves
Nicole C Fay
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0030704
P407
P577
2012-02-08T00:00:00Z