Rv1818c-encoded PE_PGRS protein of Mycobacterium tuberculosis is surface exposed and influences bacterial cell structure
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Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alphaImmunoregulatory functions and expression patterns of PE/PPE family members: Roles in pathogenicity and impact on anti-tuberculosis vaccine and drug designThe ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10Identification and Characterization of Lipase Activity and Immunogenicity of LipL from Mycobacterium tuberculosisToward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosisTranscriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosisAn immunomodulatory role for the Mycobacterium tuberculosis region of difference 1 locus proteins PE35 (Rv3872) and PPE68 (Rv3873)The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesisThe multifunctional PE_PGRS11 protein from Mycobacterium tuberculosis plays a role in regulating resistance to oxidative stressIdentification of outer membrane proteins of Mycobacterium tuberculosisThe transcriptional regulator Rv0485 modulates the expression of a pe and ppe gene pair and is required for Mycobacterium tuberculosis virulenceRv1698 of Mycobacterium tuberculosis represents a new class of channel-forming outer membrane proteinsIdentification of a novel multidrug efflux pump of Mycobacterium tuberculosisMycobacterium tuberculosis produces pili during human infectionSimple sequence proteins in prokaryotic proteomesPotential of Ca2+ in Mycobacterium tuberculosis H37Rv Pathogenesis and Survival.Mycobacterial PE/PPE proteins at the host-pathogen interface.Insights into the evolutionary history of tubercle bacilli as disclosed by genetic rearrangements within a PE_PGRS duplicated gene pair.Permeabilization of the mycobacterial envelope for protein cytolocalization studies by immunofluorescence microscopy.Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions.Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophagesImpact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis.The PGRS Domain from PE_PGRS33 of Mycobacterium tuberculosis is Target of Humoral Immune Response in Mice and Humans.Genome-wide transcription analyses in Mycobacterium tuberculosis treated with lupulone.The PE-PPE domain in mycobacterium reveals a serine α/β hydrolase fold and function: an in-silico analysisVariation of the Mycobacterium tuberculosis PE_PGRS 33 gene among clinical isolates.Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall.Comparative analysis of Mycobacterium tuberculosis pe and ppe genes reveals high sequence variation and an apparent absence of selective constraints.A PE protein expressed by Mycobacterium avium is an effective T-cell immunogen.Surface expression of MPT64 as a fusion with the PE domain of PE_PGRS33 enhances Mycobacterium bovis BCG protective activity against Mycobacterium tuberculosis in miceMycobacterium tuberculosis PE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation?Immunogenicity and reactivity of novel Mycobacterium avium subsp. paratuberculosis PPE MAP1152 and conserved MAP1156 proteins with sera from experimentally and naturally infected animals.Impact of protein domains on PE_PGRS30 polar localization in MycobacteriaThe Mycobacterium tuberculosis PE proteins Rv0285 and Rv1386 modulate innate immunity and mediate bacillary survival in macrophagesThe PE16 (Rv1430) of Mycobacterium tuberculosis is an esterase belonging to serine hydrolase superfamily of proteins.The PPE domain of PPE17 is responsible for its surface localization and can be used to express heterologous proteins on the mycobacterial surfaceVariable expression patterns of Mycobacterium tuberculosis PE_PGRS genes: evidence that PE_PGRS16 and PE_PGRS26 are inversely regulated in vivo.Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway.Mycobacterium tuberculosis Rv3402c enhances mycobacterial survival within macrophages and modulates the host pro-inflammatory cytokines production via NF-kappa B/ERK/p38 signalingMycobacterium tuberculosis SigM positively regulates Esx secreted protein and nonribosomal peptide synthetase genes and down regulates virulence-associated surface lipid synthesis
P2860
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P2860
Rv1818c-encoded PE_PGRS protein of Mycobacterium tuberculosis is surface exposed and influences bacterial cell structure
description
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Mai 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/05/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/05/01)
@nl
наукова стаття, опублікована в травні 2004
@uk
مقالة علمية (نشرت في مايو 2004)
@ar
name
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@ast
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@en
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@nl
type
label
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@ast
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@en
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@nl
prefLabel
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@ast
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@en
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@nl
P2093
P2860
P921
P3181
P1476
Rv1818c-encoded PE_PGRS protei ...... ences bacterial cell structure
@en
P2093
Alessandra Bua
Cinzia Pusceddu
Giovanni Fadda
Michael J. Brennan
Stefania Zanetti
P2860
P304
P3181
P356
10.1111/J.1365-2958.2004.04007.X
P407
P577
2004-05-01T00:00:00Z