Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning
about
Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.MEKK3 initiates transforming growth factor beta 2-dependent epithelial-to-mesenchymal transition during endocardial cushion morphogenesisTargeting BMP signalling in cardiovascular disease and anaemiaPotential Reparative Role of Resident Adult Renal Stem/Progenitor Cells in Acute Kidney InjuryCoordinating tissue interactions: Notch signaling in cardiac development and diseaseBMPs and their clinical potentialsEndocardial and epicardial epithelial to mesenchymal transitions in heart development and diseaseLoss of the cytoskeletal protein Pdlim7 predisposes mice to heart defects and hemostatic dysfunctionEmbryonic Ethanol Exposure Dysregulates BMP and Notch Signaling, Leading to Persistent Atrio-Ventricular Valve Defects in ZebrafishFunctional Analysis of Two Novel Mutations in TWIST1 Protein Motifs Found in Ventricular Septal Defect PatientsSignaling via the Tgf-beta type I receptor Alk5 in heart developmentSox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve developmentAn absence of Twist1 results in aberrant cardiac neural crest morphogenesisBMP type II receptor regulates positioning of outflow tract and remodeling of atrioventricular cushion during cardiogenesisLigand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart developmentImpairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryosTbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodelingMsx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardiumBMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve developmentBmp2 is required for cephalic neural tube closure in the mousePitx2-mediated cardiac outflow tract remodeling.Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crestZyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis.Epicardial spindle orientation controls cell entry into the myocardiumDefective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in miceReciprocal myocardial-endocardial interactions pattern the delay in atrioventricular junction conduction.A new strategy to measure intercellular adhesion forces in mature cell-cell contactsInduction of epithelial mesenchimal transition and vasculogenesis in the lenses of Dbl oncogene transgenic mice.Bmp signaling represses Vegfa to promote outflow tract cushion development.Differential functions of genes regulated by VEGF-NFATc1 signaling pathway in the migration of pulmonary valve endothelial cellsZebrafish Crip2 plays a critical role in atrioventricular valve development by downregulating the expression of ECM genes in the endocardial cushion.Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development.Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion.Periostin promotes a fibroblastic lineage pathway in atrioventricular valve progenitor cellsGenetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis.Myocardial smad4 is essential for cardiogenesis in mouse embryos.Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.β-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryosThe role of pygopus in the differentiation of intracardiac valves in Drosophila.Twist1 directly regulates genes that promote cell proliferation and migration in developing heart valves
P2860
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P2860
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/01)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في ديسمبر 2005)
@ar
name
Bmp2 is essential for cardiac ...... tion and myocardial patterning
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Bmp2 is essential for cardiac ...... tion and myocardial patterning
@en
Bmp2 is essential for cardiac ...... tion and myocardial patterning
@nl
type
label
Bmp2 is essential for cardiac ...... tion and myocardial patterning
@ast
Bmp2 is essential for cardiac ...... tion and myocardial patterning
@en
Bmp2 is essential for cardiac ...... tion and myocardial patterning
@nl
prefLabel
Bmp2 is essential for cardiac ...... tion and myocardial patterning
@ast
Bmp2 is essential for cardiac ...... tion and myocardial patterning
@en
Bmp2 is essential for cardiac ...... tion and myocardial patterning
@nl
P2093
P921
P3181
P356
P1433
P1476
Bmp2 is essential for cardiac ...... tion and myocardial patterning
@en
P2093
James F. Martin
Lijiang Ma
Mei-Fang Lu
Robert J. Schwartz
P304
P3181
P356
10.1242/DEV.02156
P407
P577
2005-12-01T00:00:00Z