Multiple functions of Jab1 are required for early embryonic development and growth potential in mice
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COP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phaseMyeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3The DenA/DEN1 Interacting Phosphatase DipA Controls Septa Positioning and Phosphorylation-Dependent Stability of Cytoplasmatic DenA/DEN1 during Fungal DevelopmentCycle inhibiting factors (cifs): cyclomodulins that usurp the ubiquitin-dependent degradation pathway of host cells.ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer DevelopmentThe murine ortholog of notchless, a direct regulator of the notch pathway in Drosophila melanogaster, is essential for survival of inner cell mass cells.Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradationCOP9 subunits 4 and 5 target soluble guanylyl cyclase α1 and p53 in prostate cancer cells.Loss of jab1 in osteochondral progenitor cells severely impairs embryonic limb development in mice.COPing with hypoxiaJAB1/CSN5: a new player in cell cycle control and cancerRefined mapping of a quantitative trait locus on chromosome 1 responsible for mouse embryonic death.Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice.Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosomeSubstrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization.Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.Revisiting the COP9 signalosome as a transcriptional regulator.p53 mediates cigarette smoke-induced apoptosis of pulmonary endothelial cells: inhibitory effects of macrophage migration inhibitor factorNeddylation and deneddylation in cardiac biologyGfer is a critical regulator of HSC proliferation.The COP9 signalosome and cullin-RING ligases in the heartThe COP9 signalosome is vital for timely repair of DNA double-strand breaks.An eight-subunit COP9 signalosome with an intact JAMM motif is required for fungal fruit body formation.CSN6 deregulation impairs genome integrity in a COP1-dependent pathwayAnalysis of RNA expression of normal and cancer tissues reveals high correlation of COP9 gene expression with respiratory chain complex components.Targeting Jab1/CSN5 in nasopharyngeal carcinomaEssential roles of Jab1 in cell survival, spontaneous DNA damage and DNA repairExpression of truncated Int6/eIF3e in mammary alveolar epithelium leads to persistent hyperplasia and tumorigenesis.Knockdown of subunit 3 of the COP9 signalosome inhibits C2C12 myoblast differentiation via NF-KappaB signaling pathwayCOP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer.The organization of a CSN5-containing subcomplex of the COP9 signalosome.THE COP9 SIGNALOSOME, A NOVEL, ESSENTIAL REGULATOR OF SKELETAL DEVELOPMENT AND TUMORIGENESIS.Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development.CSN5 specifically interacts with CDK2 and controls senescence in a cytoplasmic cyclin E-mediated manner.Identification of factors that function in Drosophila salivary gland cell death during development using proteomics.The transcriptional co-regulator Jab1 is crucial for chondrocyte differentiation in vivo.CSN6 positively regulates c-Jun in a MEKK1-dependent manner.Transcriptional repression of p27 is essential for murine embryonic developmentCops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription
P2860
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P2860
Multiple functions of Jab1 are required for early embryonic development and growth potential in mice
description
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im Oktober 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/10/08)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/10/08)
@nl
наукова стаття, опублікована в жовтні 2004
@uk
name
Multiple functions of Jab1 are ...... t and growth potential in mice
@ast
Multiple functions of Jab1 are ...... t and growth potential in mice
@en
Multiple functions of Jab1 are ...... t and growth potential in mice
@nl
type
label
Multiple functions of Jab1 are ...... t and growth potential in mice
@ast
Multiple functions of Jab1 are ...... t and growth potential in mice
@en
Multiple functions of Jab1 are ...... t and growth potential in mice
@nl
prefLabel
Multiple functions of Jab1 are ...... t and growth potential in mice
@ast
Multiple functions of Jab1 are ...... t and growth potential in mice
@en
Multiple functions of Jab1 are ...... t and growth potential in mice
@nl
P2093
P2860
P3181
P356
P1476
Multiple functions of Jab1 are ...... t and growth potential in mice
@en
P2093
Akihisa Fukumoto
Jun-Ya Kato
Kiichiro Tomoda
Noriko Yoneda-Kato
P2860
P304
43013–43018
P3181
P356
10.1074/JBC.M406559200
P407
P577
2004-10-08T00:00:00Z