Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
about
The long noncoding RNA RNCR2 directs mouse retinal cell specificationOtx2 gene deletion in adult mouse retina induces rapid RPE dystrophy and slow photoreceptor degenerationForkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitorsNegative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survivalBEST1 expression in the retinal pigment epithelium is modulated by OTX family membersAP2 transcription factor induces apoptosis in retinoblastoma cellsHeterozygous mutations of OTX2 cause severe ocular malformationsExpression of the homeobox genes OTX2 and OTX1 in the early developing human brainA novel dominant negative mutation of OTX2 associated with combined pituitary hormone deficiencyRetinoic acid regulates the expression of photoreceptor transcription factor NRLSynaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant miceT-STAG: resource and web-interface for tissue-specific transcripts and genesPhotoreceptor cell fate specification in vertebratesMinireview: the role of nuclear receptors in photoreceptor differentiation and diseaseCommon transcriptional mechanisms for visual photoreceptor cell differentiation among PancrustaceansHomeobox genes and melatonin synthesis: regulatory roles of the cone-rod homeobox transcription factor in the rodent pineal glandBiology and therapy of inherited retinal degenerative disease: insights from mouse modelsCloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cellsRetinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor developmentPanky, a novel photoreceptor-specific ankyrin repeat protein, is a transcriptional cofactor that suppresses CRX-regulated photoreceptor genesAP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesisA comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursorsEpigenomic landscapes of retinal rods and conesA novel pineal-specific product of the oligopeptide transporter PepT1 gene: circadian expression mediated by cAMP activation of an intronic promoterRegulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRLThe photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genesThe orphan nuclear hormone receptor ERRbeta controls rod photoreceptor survival.Evolution of the eye transcriptome under constant darkness in Sinocyclocheilus cavefishChoroid-plexus-derived Otx2 homeoprotein constrains adult cortical plasticityNight/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling.Cone and rod photoreceptor transplantation in models of the childhood retinopathy Leber congenital amaurosis using flow-sorted Crx-positive donor cells.NeuroD1 is required for survival of photoreceptors but not pinealocytes: results from targeted gene deletion studies.Cone photoreceptor types in zebrafish are generated by symmetric terminal divisions of dedicated precursors.Temporal and spatial delineation of mouse Otx2 functions by conditional self-knockoutSterile alpha motif containing 7 (samd7) is a novel crx-regulated transcriptional repressor in the retina.Requirement of histone deacetylase activity for the expression of critical photoreceptor genesThe cis-regulatory logic of the mammalian photoreceptor transcriptional network.A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors.Individual retinal progenitor cells display extensive heterogeneity of gene expression.CRX is a diagnostic marker of retinal and pineal lineage tumors
P2860
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P2860
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
description
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im November 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/12/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/12/01)
@nl
наукова стаття, опублікована в грудні 2003
@uk
مقالة علمية (نشرت في ديسمبر 2003)
@ar
name
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@ast
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@en
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@nl
type
label
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@ast
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@en
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@nl
prefLabel
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@ast
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@en
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@nl
P2093
P921
P3181
P356
P1433
P1476
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
@en
P2093
Akihiro Nishida
Akiko Furukawa
Shinichi Aizawa
Takahisa Furukawa
Yasuo Tano
P2888
P304
P3181
P356
10.1038/NN1155
P407
P577
2003-11-16T00:00:00Z