Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis
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Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determinationBuilding the mammalian testis: origins, differentiation, and assembly of the component cell populationsIndian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermisMale sex determination: insights into molecular mechanismsTargeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsCell fate commitment during mammalian sex determinationHow to make a gonad: cellular mechanisms governing formation of the testes and ovariesSex and hedgehog: roles of genes in the hedgehog signaling pathway in mammalian sexual differentiationRapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryosMammalian sex determination—insights from humans and mice.Disruption of testis cords by cyclopamine or forskolin reveals independent cellular pathways in testis organogenesisGenetic control of testis developmentParacrine sonic hedgehog signaling contributes significantly to acquired steroidogenesis in the prostate tumor microenvironmentGLP-1: a novel zinc finger protein required in somatic cells of the gonad for germ cell developmentEliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine developmentGPR56 is essential for testis development and male fertility in micePdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonadSteroidogenic factor 1 differentially regulates fetal and adult leydig cell development in male miceDynamic changes in fetal Leydig cell populations influence adult Leydig cell populations in miceSteroidogenic factor-1 (SF-1)-driven differentiation of murine embryonic stem (ES) cells into a gonadal lineageEpithelial-mesenchymal crosstalk in Wolffian duct and fetal testis cord development.Action mechanism of inhibin α-subunit on the development of Sertoli cells and first wave of spermatogenesis in miceLoss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testisTestosterone levels influence mouse fetal Leydig cell progenitors through notch signaling.Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation.Fetal Leydig cell origin and development.An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in miceMinireview: steroidogenic factor 1: its roles in differentiation, development, and diseaseIdentification of Hedgehog signaling outcomes in mouse testis development using a hanging drop-culture systemCellular mechanisms of sex determination in the red-eared slider turtle, Trachemys scripta.The road to maleness: from testis to Wolffian duct.Insights into the Development of the Adult Leydig Cell Lineage from Stem Leydig Cells.Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells.Desert hedgehog is a mammal-specific gene expressed during testicular and ovarian development in a marsupial.Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish.The transcription factor FOXL2 mobilizes estrogen signaling to maintain the identity of ovarian granulosa cells.Regulation of male sex determination: genital ridge formation and Sry activation in mice.Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals.Mouse testis development and function are differently regulated by follicle-stimulating hormone receptors signaling during fetal and prepubertal life.
P2860
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P2860
Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis
description
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Juni 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/06/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/06/01)
@nl
наукова стаття, опублікована в червні 2002
@uk
مقالة علمية (نشرت في يونيو 2002)
@ar
name
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@ast
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@en
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@nl
type
label
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@ast
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@en
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@nl
prefLabel
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@ast
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@en
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@nl
P2860
P3181
P356
P1433
P1476
Desert Hedgehog/Patched 1 sign ...... l fate in testis organogenesis
@en
P2093
Blanche Capel
Wendy Whoriskey
P2860
P304
P3181
P356
10.1101/GAD.981202
P577
2002-06-01T00:00:00Z