Deficiency in Crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice
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The Family of Crumbs Genes and Human DiseaseProtein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulationCRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium.Expansion of phenotype and genotypic data in CRB2-related syndromeCRB2 mutations produce a phenotype resembling congenital nephrosis, Finnish type, with cerebral ventriculomegaly and raised alpha-fetoprotein.Apical localisation of crumbs in the boundary cells of the Drosophila hindgut is independent of its canonical interaction partner stardustThe C. elegans Crumbs family contains a CRB3 homolog and is not essential for viability.CRB3A Controls the Morphology and Cohesion of Cancer Cells through Ehm2/p114RhoGEF-Dependent Signaling.Mouse Crumbs3 sustains epithelial tissue morphogenesis in vivoCrumbs is an essential regulator of cytoskeletal dynamics and cell-cell adhesion during dorsal closure in Drosophila.Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells.Crumbs3 is essential for proper epithelial development and viabilityThe Crumbs_C isoform of Drosophila shows tissue- and stage-specific expression and prevents light-dependent retinal degeneration.The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy.Cell polarity and cystic kidney disease.Evolution and cell physiology. 4. Why invent yet another protein complex to build junctions in epithelial cells?The multiple roles of epidermal growth factor repeat O-glycans in animal development.Epithelial-mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis.Cell polarity proteins and spermatogenesis.Cross talk between the Crumbs complex and Hippo signaling in renal epithelial cells.Distinct functions of Crumbs regulating slit diaphragms and endocytosis in Drosophila nephrocytes.The core planar cell polarity gene, Vangl2, maintains apical-basal organisation of the corneal epithelium.Molecular components and polarity of radial glial cells during cerebral cortex development.CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice.An epigenetic signature of developmental potential in neural stem cells and early neurons.Placentation defects are highly prevalent in embryonic lethal mouse mutants.Expanding the phenotype of CRB2 mutations - A new ciliopathy syndrome?A case report of CRB2 mutation identified in a Chinese boy with focal segmental glomerulosclerosisExpression and localization of the polarity protein CRB2 in adult mouse brain: a comparison with the CRB1 mutant mouse model
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P2860
Deficiency in Crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice
description
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
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im Dezember 2011 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2011/12/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/12/01)
@nl
наукова стаття, опублікована в грудні 2011
@uk
مقالة علمية (نشرت في ديسمبر 2011)
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name
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@ast
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@en
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@nl
type
label
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@ast
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@en
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@nl
prefLabel
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@ast
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@en
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@nl
P2093
P2860
P3181
P356
P1476
Deficiency in Crumbs homolog 2 ...... in embryonic lethality in mice
@en
P2093
Jaakko Patrakka
Karl Tryggvason
Masatoshi Nukui
Seppo Vainio
Timo Pikkarainan
Timo Pikkarainen
Zhijie Xiao
P2860
P304
P3181
P356
10.1002/DVDY.22778
P577
2011-12-01T00:00:00Z