SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
about
Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha SignalingCD47 knockout mice exhibit improved recovery from spinal cord injury.The SIRP family of receptors and immune regulationSHPS-1, a multifunctional transmembrane glycoproteinMacrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement.Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein α (SIRPα) signaling.Genome-wide isolation of growth and obesity QTL using mouse speed congenic strains.Signal regulatory protein alpha negatively regulates beta2 integrin-mediated monocyte adhesion, transendothelial migration and phagocytosis.Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.The absence of CD47 promotes nerve fiber growth from cultured ventral mesencephalic dopamine neuronsGenetic interaction between integrins and moleskin, a gene encoding a Drosophila homolog of importin-7.A discoidin domain receptor 1/SHP-2 signaling complex inhibits alpha2beta1-integrin-mediated signal transducers and activators of transcription 1/3 activation and cell migration.Corticotropin-releasing hormone modulates human trophoblast invasion through carcinoembryonic antigen-related cell adhesion molecule-1 regulationSignal regulatory protein-α protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signalingNon-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and SpleenGab1 mediates hepatocyte growth factor-stimulated mitogenicity and morphogenesis in multipotent myeloid cells.Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2LPS-induced down-regulation of signal regulatory protein {alpha} contributes to innate immune activation in macrophages.Subcellular targeting of oxidants during endothelial cell migrationPrion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling.Signal regulatory protein α regulates the homeostasis of T lymphocytes in the spleen.SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells.Noonan syndrome-associated SHP-2/Ptpn11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated ERK activationSHPS-1 and a synthetic peptide representing its ITIM inhibit the MyD88, but not TRIF, pathway of TLR signaling through activation of SHP and PI3K in THP-1 cells.Promotion of neurite and filopodium formation by CD47: roles of integrins, Rac, and Cdc42.Role of the CD47-SHPS-1 system in regulation of cell migrationSHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway.Ectodomain shedding of SHPS-1 and its role in regulation of cell migration.Resistance of B16 melanoma cells to CD47-induced negative regulation of motility as a result of aberrant N-glycosylation of SHPS-1.Ubiquitination-mediated regulation of biosynthesis of the adhesion receptor SHPS-1 in response to endoplasmic reticulum stress.Specific SHP-2 partitioning in raft domains triggers integrin-mediated signaling via Rho activation.Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+) CD11b(+) DCs in the intestinal lamina propriaSignal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathwaysSignal regulatory proteins (SIRPS) are secreted presynaptic organizing moleculesRole of CD47 and Signal Regulatory Protein Alpha (SIRPα) in Regulating the Clearance of Viable or Aged Blood Cells.Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs.Metallic nanoparticles reduce the migration of human fibroblasts in vitroDonor SIRPα polymorphism modulates the innate immune response to allogeneic grafts.Modulation of alpha-catenin Tyr phosphorylation by SHP2 positively effects cell transformation induced by the constitutively active FGFR3.Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase.
P2860
Q27306859-81EBD82C-0A9D-4AE5-A71D-5B57924C21E0Q27863417-93191AE1-E011-4BD6-8535-942626823789Q28239784-8732DAA0-36B4-487C-AEC2-5C936482292EQ28611511-EFEF861A-1BDB-4073-B14D-5C7C48097C66Q30533919-BB55EB6C-43A5-4D10-93DD-ADE9E4DDCF58Q31128487-CABA6F46-05AF-4C36-8707-4400539A5915Q33241997-39769777-52EF-49A3-8F3B-6422D7D32FFEQ33372339-DDB053C0-6CDB-4F6B-A504-81779E47792FQ33877092-40DBCF61-99CC-461A-894D-22A152361611Q34438025-9426DCE1-DCEA-4D7C-A6DF-2F2D8F86263BQ34615984-418A849C-FF5C-4E01-BF9F-E6449C418BA1Q34661632-76D4941D-B6DA-4A7A-A37D-65CD7A76001FQ35070793-0951037B-B0D8-484D-A6AC-91AF9AABF92AQ35576675-6C672BEE-3A58-4EBA-8800-AABF555E3D1AQ35722965-77554D88-030B-4012-A902-480A9E4043E6Q36086815-1450F02C-3867-4943-B993-15C7F9EA36E2Q36097610-59D00D2D-74D5-45BB-A3FB-DDF2DD7072ACQ36229103-1DCB05B8-7783-4FA1-B1DE-2AFF5C36ED0FQ36320521-4E63D064-6E22-4B7B-9F96-EE0C825939B4Q36381643-67EA3ED9-1120-4CFA-9921-CA600891F077Q36382863-E1A8124B-2CED-47D0-B79B-29755F011F33Q37322155-AD9A94DB-AAB7-401B-A99D-01DDCD31E12CQ38631424-027E10B7-8ADE-40B0-8702-E4DE3DC40BA0Q39211459-9C11AA4B-7621-457B-B95A-18671F5760F0Q39285163-965A226D-BA74-499A-88BB-F5908116C105Q39758938-D123AEDC-3AAA-4FB5-93B2-33FA05C35DCBQ40550696-05D2C9E5-A409-4B95-ADF5-7FD8CC6929F4Q40559733-2008E855-9067-4F7E-9157-A33362A39DE5Q40596491-172D41A3-CEAB-4E98-A2CD-3FFD4AB681A0Q40602813-F563E874-2374-4E9B-91DA-DBC4B86AEA76Q40737797-A6CD8B67-4E30-437A-81F9-961794CA5384Q41733543-FC94E0AD-4DCB-4D15-BC69-D1A4285115E9Q42086318-3999F83C-07FB-43BD-8F4D-2C430DCA328EQ42125640-5DF5BF02-5823-4260-A576-782E79311326Q42148438-F56D9293-DEE3-4265-9FAF-1D53E2E17512Q42151923-38C7DDB8-6005-4221-8E99-176DBEE7CAB6Q42315708-9020B1D8-F655-4361-B404-CDF0ACE216C0Q42381401-EE791DF7-6118-4F2B-BFBB-CB5095CC9274Q42800448-FCBCC632-3DF4-4AA1-86E5-0ED69E5B99E5Q43166807-53459B20-865A-46EA-8994-83CCDC83DC5C
P2860
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
description
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Dezember 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/12/15)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/12/15)
@nl
наукова стаття, опублікована в грудні 2000
@uk
مقالة علمية (نشرت في 15-12-2000)
@ar
name
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@ast
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@en
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@nl
type
label
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@ast
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@en
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@nl
prefLabel
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@ast
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@en
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@nl
P2093
P2860
P356
P1433
P1476
SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
@en
P2093
K. Fukunaga
K. Inagaki
T. Hosooka
T. Matozaki
T. Noguchi
P2860
P304
P356
10.1093/EMBOJ/19.24.6721
P407
P577
2000-12-15T00:00:00Z