Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart
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A role for Tbx5 in proepicardial cell migration during cardiogenesisBrachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activityA gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defectsMutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathyTbx20 regulates a genetic program essential to adult mouse cardiomyocyte functionMesenchymal Stem Cells for Cardiac Regenerative Therapy: Optimization of Cell Differentiation StrategyThe T-box gene family: emerging roles in development, stem cells and cancerFunctional cardiomyocytes derived from Isl1 cardiac progenitors via Bmp4 stimulationIn Vitro Differentiation of First Trimester Human Umbilical Cord Perivascular Cells into Contracting Cardiomyocyte-Like Cells.Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5Gata6 is an important regulator of mouse pancreas developmentDifferential expression and function of Tbx5 and Tbx20 in cardiac developmentLack of genetic interaction between Tbx20 and Tbx3 in early mouse heart developmentNanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cellsAsh2l interacts with Tbx1 and is required during early embryogenesisCharacterization of the novel interaction between muskelin and TBX20, a critical cardiogenic transcription factorTranscriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressorsT-box genes coordinate regional rates of proliferation and regional specification during cardiogenesisT-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migrationTbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21GATA4 is essential for formation of the proepicardium and regulates cardiogenesisCollaboratively charting the gene-to-phenotype network of human congenital heart defectsISL1 directly regulates FGF10 transcription during human cardiac outflow formation.Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence dataEfficient array-based identification of novel cardiac genes through differentiation of mouse ESCs.Molecular genetics of congenital atrial septal defectsA Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.TBX20 loss-of-function mutation responsible for familial tetralogy of Fallot or sporadic persistent truncus arteriosusPitx2-dependent occupancy by histone deacetylases is associated with T-box gene regulation in mammalian abdominal tissue.Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects.Synergistic activation of cardiac genes by myocardin and Tbx5.Cardiac cell lineages that form the heart.A novel variant in TBX20 (p.D176N) identified by whole-exome sequencing in combination with a congenital heart disease related gene filter is associated with familial atrial septal defect.Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and functionLINE-1 methylation status and its association with tetralogy of fallot in infantsIn vitro site selection of a consensus binding site for the Drosophila melanogaster Tbx20 homolog midlineDevelopmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factorsTranscription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease.Contribution of distinct homeodomain DNA binding specificities to Drosophila embryonic mesodermal cell-specific gene expression programs.DNA methylation status of NKX2-5, GATA4 and HAND1 in patients with tetralogy of fallot.
P2860
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P248
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P2860
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart
description
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Oktober 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/10/15)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/10/15)
@nl
наукова стаття, опублікована в жовтні 2003
@uk
مقالة علمية (نشرت في 15-10-2003)
@ar
name
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@ast
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@en
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@nl
type
label
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@ast
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@en
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@nl
prefLabel
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@ast
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@en
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@nl
P2093
P50
P921
P3181
P1476
Cardiac T-box factor Tbx20 dir ...... ession in the developing heart
@en
P2093
Aaron M Zorn
Fiona A Stennard
Karen Niederreither
Lachlan P A McDonald
Pascal Dolle
Saskia J P Haast
Scott Rankin
P304
P3181
P356
10.1016/S0012-1606(03)00385-3
P407
P577
2003-10-01T00:00:00Z