Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3
about
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiationGATA-3 links tumor differentiation and dissemination in a luminal breast cancer modelExpression of the T-cell transcription factors, GATA-3 and T-bet, in the neoplastic cells of Hodgkin lymphomasCell fate decision: T-helper 1 and 2 subsets in immune responses.Genetically manipulated mouse models of lung disease: potential and pitfallsSuppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic diseaseGene expression profiling of lymphoblasts from autistic and nonaffected sib pairs: altered pathways in neuronal development and steroid biosynthesisActivation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthmaIndoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammationDifferentiation of effector CD4 T cell populations (*)GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses.GATA3: a master of many trades in immune regulation.The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammationTLR4/MyD88-induced CD11b+Gr-1 int F4/80+ non-migratory myeloid cells suppress Th2 effector function in the lung.From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation.src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation.An important regulatory role for CD4+CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel diseaseInducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia.GATA3 up-regulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cells.IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cellsTransforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis.T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.High IFN-γ and low SLPI mark severe asthma in mice and humans.Transcriptional regulation of Th2 cell differentiation.Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression.Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiationInterleukin 18 acts on memory T helper cells type 1 to induce airway inflammation and hyperresponsiveness in a naive host mouse.Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environmentGATA-3 deficiency abrogates the development and maintenance of T helper type 2 cellsCurrent concepts of severe asthmaSteady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cellsSTAT6 activation confers upon T helper cells resistance to suppression by regulatory T cells.Treatment of allergic inflammation and hyperresponsiveness by a simple compound, Bavachinin, isolated from Chinese herbs.Transcriptional regulation of T helper type 2 differentiation.Emerging molecular phenotypes of asthma.NFκB attenuates IL-5 production and upregulates T-box transcription factors in Th2-like T cellsTh2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB.Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs
P2860
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P2860
Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3
description
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
@ast
im Oktober 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/10/01)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/10/01)
@nl
наукова стаття, опублікована в жовтні 1999
@uk
مقالة علمية (نشرت في أكتوبر 1999)
@ar
name
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@ast
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@en
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@nl
type
label
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@ast
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@en
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@nl
prefLabel
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@ast
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@en
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@nl
P2093
P921
P1433
P1476
Inhibition of allergic inflamm ...... nant-negative mutant of GATA-3
@en
P2093
D. H. Zhang
P304
P407
P577
1999-10-01T00:00:00Z