Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
about
Delayed and accelerated aging share common longevity assurance mechanismsAltered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type miceThioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf miceExtension of chronological life span in yeast by decreased TOR pathway signalingEndocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouseTelomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancerSingle-gene mutations and healthy ageing in mammalsGrowth hormone and aging: a challenging controversyRole of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models.Biological approaches to mechanistically understand the healthy life span extension achieved by calorie restriction and modulation of hormonesBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesHealthy aging: is smaller better? - a mini-reviewGrowth hormone in the aging maleDoes reduced IGF-1R signaling in Igf1r+/- mice alter aging?Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanismLinks between growth hormone and aging.Insulin, aging, and the brain: mechanisms and implicationsMinireview: The Complexities of IGF/Insulin Signaling in Aging: Why Flies and Worms Are Not HumansThe somatotropic axis and longevity in mice'Accelerated aging': a primrose path to insight?Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in miceEffects of aging and caloric restriction on the gene expression of Foxo1, 3, and 4 (FKHR, FKHRL1, and AFX) in the rat skeletal musclesOrganization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and LongevityUneven futures of human lifespans: reckonings from Gompertz mortality rates, climate change, and air pollutionBig mice die young but large animals live longerLiver-derived IGF-I regulates mean life span in miceChanges in gene expression associated with aging commonly originate during juvenile growthFibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stressExtending life: scientific prospects and political obstaclesIGF-1 receptor regulates lifespan and resistance to oxidative stress in miceModulation of mammalian life span by the short isoform of p53.Running on empty: how p53 controls INS/IGF signaling and affects life spanHuman longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studiesHypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRHDauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.Gene expression profiling of long-lived dwarf mice: longevity-associated genes and relationships with diet, gender and aging.Two-year body composition analyses of long-lived GHR null mice.Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic.Human insulin/IGF-1 and familial longevity at middle age.The effect of caloric restriction interventions on growth hormone secretion in nonobese men and women.
P2860
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P2860
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
description
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2001
@ast
im Juni 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/06/05)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/06/05)
@nl
наукова стаття, опублікована в червні 2001
@uk
name
Lifespan extension and delayed ...... s in growth hormone production
@ast
Lifespan extension and delayed ...... s in growth hormone production
@en
Lifespan extension and delayed ...... s in growth hormone production
@nl
type
label
Lifespan extension and delayed ...... s in growth hormone production
@ast
Lifespan extension and delayed ...... s in growth hormone production
@en
Lifespan extension and delayed ...... s in growth hormone production
@nl
prefLabel
Lifespan extension and delayed ...... s in growth hormone production
@ast
Lifespan extension and delayed ...... s in growth hormone production
@en
Lifespan extension and delayed ...... s in growth hormone production
@nl
P2093
P2860
P3181
P356
P1476
Lifespan extension and delayed ...... s in growth hormone production
@en
P2093
D. E. Harrison
J. Papaconstantinou
K. Flurkey
R. A. Miller
P2860
P304
P3181
P356
10.1073/PNAS.111158898
P407
P577
2001-06-05T00:00:00Z