How defects in central tolerance impinge on a deficiency in regulatory T cells
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Lymphopenia-induced proliferation in aire-deficient mice helps to explain their autoimmunity and differences from human patientsAn intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoiresRegulatory T cells: mechanisms of differentiation and functionThe Biology of Autoimmune Response in the Scurfy Mice that Lack the CD4+Foxp3+ Regulatory T-CellsA novel role of IL-2 in organ-specific autoimmune inflammation beyond regulatory T cell checkpoint: both IL-2 knockout and Fas mutation prolong lifespan of Scurfy mice but by different mechanismsIL-2: a two-faced master regulator of autoimmunityGenetic control of the inflammatory T-cell response in regulatory T-cell deficient scurfy mice.X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms.IL-2 regulates CD103 expression on CD4+ T cells in Scurfy mice that display both CD103-dependent and independent inflammationPervasive and stochastic changes in the TCR repertoire of regulatory T-cell-deficient mice.Rapid and selective expansion of nonclonotypic T cells in regulatory T cell-deficient, foreign antigen-specific TCR-transgenic scurfy mice: antigen-dependent expansion and TCR analysis.Regulation of multi-organ inflammation in the regulatory T cell-deficient scurfy mice.Large functional repertoire of regulatory T-cell suppressible autoimmune T cells in scurfy mice.Glutamic acid decarboxylase-derived epitopes with specific domains expand CD4(+)CD25(+) regulatory T cells.Bidirectional homing of Tregs between the skin and lymph nodesInterleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis.Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development.Immune tolerance induction by integrating innate and adaptive immune regulators.Regulatory T cells and Foxp3Defective regulatory and effector T cell functions in patients with FOXP3 mutations.Control of regulatory T cell lineage commitment and maintenance.CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2Regulatory T cells for tolerance therapy: revisiting the concept.Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3Breakdown in peripheral tolerance in type 1 diabetes in mice and humansFull restoration of peripheral Foxp3+ regulatory T cell pool by radioresistant host cells in scurfy bone marrow chimeras.Following the fate of one insulin-reactive CD4 T cell: conversion into Teffs and Tregs in the periphery controls diabetes in NOD mice.Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease.Reduced TCR signaling potential impairs negative selection but does not result in autoimmune disease.From biomarkers to a clue of biology: a computation-aided perspective of immune gene expression profiles in human type 1 diabetes.Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.The dynamics of effector T cells and Foxp3+ regulatory T cells in the promotion and regulation of autoimmune encephalomyelitisThe role of regulatory T cells in alloantigen tolerance.Regulatory T cells in the prevention of mucosal inflammatory diseases: patrolling the border.Studies in mice deficient for the autoimmune regulator (Aire) and transgenic for the thyrotropin receptor reveal a role for Aire in tolerance for thyroid autoantigensMolecular orchestration of differentiation and function of regulatory T cells.Shaping the T-cell repertoire: a matter of life and death.AIRE expands: new roles in immune tolerance and beyond.Restoring Regulatory T Cells in Type 1 Diabetes.An immunologic homunculus for type 1 diabetes.
P2860
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P2860
How defects in central tolerance impinge on a deficiency in regulatory T cells
description
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2005
@ast
im Oktober 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/10/11)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/10/11)
@nl
наукова стаття, опублікована в жовтні 2005
@uk
name
How defects in central tolerance impinge on a deficiency in regulatory T cells
@ast
How defects in central tolerance impinge on a deficiency in regulatory T cells
@en
How defects in central tolerance impinge on a deficiency in regulatory T cells
@nl
type
label
How defects in central tolerance impinge on a deficiency in regulatory T cells
@ast
How defects in central tolerance impinge on a deficiency in regulatory T cells
@en
How defects in central tolerance impinge on a deficiency in regulatory T cells
@nl
prefLabel
How defects in central tolerance impinge on a deficiency in regulatory T cells
@ast
How defects in central tolerance impinge on a deficiency in regulatory T cells
@en
How defects in central tolerance impinge on a deficiency in regulatory T cells
@nl
P2093
P2860
P921
P356
P1476
How defects in central tolerance impinge on a deficiency in regulatory T cells
@en
P2093
Christophe Benoist
Diane Mathis
Zhibin Chen
P2860
P304
14735–14740
P356
10.1073/PNAS.0507014102
P407
P577
2005-10-11T00:00:00Z