Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis
about
Upstream regulatory role for XIAP in receptor-mediated apoptosisBile acids: regulation of apoptosis by ursodeoxycholic acidCaspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosolA novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLOModeling a snap-action, variable-delay switch controlling extrinsic cell deathDeletion of Bid impedes cell proliferation and hepatic carcinogenesisBid activation in kidney cells following ATP depletion in vitro and ischemia in vivoModulating cell-to-cell variability and sensitivity to death ligands by co-drugging.Role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning.Quantitative analysis of pathways controlling extrinsic apoptosis in single cellsMutations to bid cleavage sites protect hepatocytes from apoptosis after ischemia/reperfusion injuryHepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice.XIAP discriminates between type I and type II FAS-induced apoptosis.Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytesCrude extract of Rheum palmatum L induced cell death in LS1034 human colon cancer cells acts through the caspase-dependent and -independent pathways.Stimulation of Wnt/β-catenin signaling pathway with Wnt agonist reduces organ injury after hemorrhagic shock.Bid-independent mitochondrial activation in tumor necrosis factor alpha-induced apoptosis and liver injuryFractional killing arises from cell-to-cell variability in overcoming a caspase activity thresholdBid-cardiolipin interaction at mitochondrial contact site contributes to mitochondrial cristae reorganization and cytochrome C releaseCells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes.Promotion of Fas-mediated apoptosis in Type II cells by high doses of hepatocyte growth factor bypasses the mitochondrial requirement.Genetic delineation of the pathways mediated by bid and JNK in tumor necrosis factor-alpha-induced liver injury in adult and embryonic mice.Fas and TNFR1, but not cytolytic granule-dependent mechanisms, mediate clearance of murine liver adenoviral infectionExpression of X-linked inhibitor-of-apoptosis protein in hepatocellular carcinoma promotes metastasis and tumor recurrence.Caspase-9 activation by the apoptosome is not required for fas-mediated apoptosis in type II Jurkat cells.Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications.Rejuvenating Bi(d)ology.Surviving apoptosis: life-death signaling in single cells.Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes.Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway.Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation.Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway.Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma.Targeting and amplification of immune killing of tumor cells by pro-Smac.Bid-mediated mitochondrial pathway is critical to ischemic neuronal apoptosis and focal cerebral ischemia.Mitochondrially localized active caspase-9 and caspase-3 result mostly from translocation from the cytosol and partly from caspase-mediated activation in the organelle. Lack of evidence for Apaf-1-mediated procaspase-9 activation in the mitochondriaInhibition of γ-secretase activity synergistically enhances tumour necrosis factor-related apoptosis-inducing ligand induced apoptosis in T-cell acute lymphoblastic leukemia cells via upregulation of death receptor 5Bid agonist regulates murine hepatocyte proliferation by controlling endoplasmic reticulum calcium homeostasis.Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis.Hypoxic preconditioning potentiates the trophic effects of mesenchymal stem cells on co-cultured human primary hepatocytes.
P2860
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P2860
Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis
description
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im Juli 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/07/26)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/07/26)
@nl
наукова стаття, опублікована в липні 2002
@uk
name
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@ast
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@en
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@nl
type
label
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@ast
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@en
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@nl
prefLabel
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@ast
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@en
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@nl
P2093
P921
P356
P1476
Relief of extrinsic pathway in ...... -mediated hepatocyte apoptosis
@en
P2093
Chunying Du
Diane K. Kuharsky
Hannah Rabinowich
Shuchen Li
Tae-Hyoung Kim
Xiao-Ming Yin
Yongge Zhao
P304
26912–26920
P356
10.1074/JBC.M200726200
P407
P577
2002-07-26T00:00:00Z