Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling
about
A novel role of Sprouty 2 in regulating cellular apoptosisExpression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomasMolecular mechanisms of inner ear developmentWhere hearing starts: the development of the mammalian cochleaFgf10 is required for specification of non-sensory regions of the cochlear epithelium.Morphogenesis and cell fate determination within the adaxial cell equivalence group of the zebrafish myotomeDifferentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signalA functional interaction between sprouty proteins and caveolin-1Canal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activityHey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of CortiDisruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal patterning, and hearing impairmentFgf20 is required for sensory epithelial specification in the developing cochleaEnamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisorsControl of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shapeRegulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signalingShaping sound in space: the regulation of inner ear patterningThe branching programme of mouse lung developmentTranscriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing.MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear.Quantitative High-Resolution Cellular Map of the Organ of Corti.MAP3K1 function is essential for cytoarchitecture of the mouse organ of Corti and survival of auditory hair cells.LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochleaCross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear.Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates.Regulation of sprouty stability by Mnk1-dependent phosphorylation.Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochleaSelective ablation of pillar and deiters' cells severely affects cochlear postnatal development and hearing in mice.Fgf signaling regulates development and transdifferentiation of hair cells and supporting cells in the basilar papillaFilling the silent void: genetic therapies for hearing impairment.Sprouty genes are essential for the normal development of epibranchial ganglia in the mouse embryoPolygenic inheritance of sensorineural hearing loss (Snhl2, -3, and -4) and organ of Corti patterning defect in the ALR/LtJ mouse strainNoncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39.Hearing loss in a mouse model of Muenke syndromeExpression of ERK signaling inhibitors Dusp6, Dusp7, and Dusp9 during mouse ear development.Expression of Prox1 during mouse cochlear development.Cooperative and independent functions of FGF and Wnt signaling during early inner ear development.The VASP-Spred-Sprouty domain puzzle.Conditional expression of Spry1 in neural crest causes craniofacial and cardiac defects.Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea.The Interaction of Genetic Background and Mutational Effects in Regulation of Mouse Craniofacial Shape.
P2860
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P2860
Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling
description
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im April 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/04/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/04/01)
@nl
наукова стаття, опублікована у квітні 2005
@uk
مقالة علمية (نشرت في أبريل 2005)
@ar
name
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@ast
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@en
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@nl
type
label
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@ast
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@en
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@nl
prefLabel
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@ast
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@en
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@nl
P3181
P1433
P1476
Sprouty2, a mouse deafness gen ...... by antagonizing FGF signaling
@en
P2093
George Minowada
Katherine Shim
P304
P3181
P356
10.1016/J.DEVCEL.2005.02.009
P407
P577
2005-04-01T00:00:00Z