The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice
about
Tumor microenvironment and neurofibromatosis type I: connecting the GAPsCardiomyocyte cyclooxygenase-2 influences cardiac rhythm and functionRASopathies: unraveling mechanisms with animal modelsRas oncogenes: split personalitiesCardiac and vascular functions of the zebrafish orthologues of the type I neurofibromatosis gene NFI.Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis.Neoplasms associated with germline and somatic NF1 gene mutationsLoss of NF1 expression in human endothelial cells promotes autonomous proliferation and altered vascular morphogenesis.Calcium-mediated histone modifications regulate alternative splicing in cardiomyocytes.Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation.Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome.Extracranial vertebral artery involvement in neurofibromatosis type I. Report of four cases and literature review.Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos.The Ras GTPase-activating protein neurofibromin 1 promotes the positive selection of thymocytes.Neurofibromin regulates somatic growth through the hypothalamic-pituitary axisCardiomyocyte-specific loss of neurofibromin promotes cardiac hypertrophy and dysfunction.Emerging genotype-phenotype relationships in patients with large NF1 deletions.Nonredundant functions for Ras GTPase-activating proteins in tissue homeostasis.Oligodendrocyte progenitor cell numbers and migration are regulated by the zebrafish orthologs of the NF1 tumor suppressor geneSynergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain.Combinatorial therapeutic targeting of BMP2 and MEK-ERK pathways in NF1-associated malignant peripheral nerve sheath tumors.Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization.
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P2860
The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice
description
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
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im September 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2006/09/01)
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vědecký článek publikovaný v roce 2006
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wetenschappelijk artikel (gepubliceerd op 2006/09/01)
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наукова стаття, опублікована у вересні 2006
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مقالة علمية (نشرت في سبتمبر 2006)
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name
The neurofibromin GAP-related ...... crest development in Nf1 mice
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The neurofibromin GAP-related ...... crest development in Nf1 mice
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The neurofibromin GAP-related ...... crest development in Nf1 mice
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type
label
The neurofibromin GAP-related ...... crest development in Nf1 mice
@ast
The neurofibromin GAP-related ...... crest development in Nf1 mice
@en
The neurofibromin GAP-related ...... crest development in Nf1 mice
@nl
prefLabel
The neurofibromin GAP-related ...... crest development in Nf1 mice
@ast
The neurofibromin GAP-related ...... crest development in Nf1 mice
@en
The neurofibromin GAP-related ...... crest development in Nf1 mice
@nl
P2093
P2860
P3181
P356
P1476
The neurofibromin GAP-related ...... crest development in Nf1 mice
@en
P2093
Fraz A. Ismat
Jonathan A. Epstein
Junwang Xu
Min Min Lu
P2860
P304
P3181
P356
10.1172/JCI28341
P407
P577
2006-09-01T00:00:00Z