Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury
about
Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assaysMicroglia in the spinal cord and neuropathic painBrain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic painCCL2 promotes P2X4 receptor trafficking to the cell surface of microgliaP2X4 receptors in activated C8-B4 cells of cerebellar microglial origin.Lyn kinase enhanced hepatic fibrosis by modulating the activation of hepatic stellate cells.Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional rolesNeuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development.Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathwaysIFN-gamma receptor signaling mediates spinal microglia activation driving neuropathic painP2X4R+ microglia drive neuropathic pain.Neuron-glia crosstalk gets serious: role in pain hypersensitivity.Effect of subcutaneous treatment with human umbilical cord blood-derived multipotent stem cells on peripheral neuropathic pain in rats.Dysregulated Src upregulation of NMDA receptor activity: a common link in chronic pain and schizophrenia.P2X receptor antagonists for pain management: examination of binding and physicochemical properties.ATP receptors gate microglia signaling in neuropathic pain.P2X4 purinoceptor signaling in chronic pain.Microglia and intractable chronic pain.Neurotransmitter signaling in the pathophysiology of microglia.P2X4 receptors and neuropathic pain.The purinergic system and glial cells: emerging costars in nociception.The protein-tyrosine phosphatase DEP-1 promotes migration and phagocytic activity of microglial cells in part through negative regulation of fyn tyrosine kinase.P2 receptors, microglial cytokines and chemokines, and neuropathic pain.Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex.Purinergic signaling in microglia in the pathogenesis of neuropathic pain.Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions.P2X receptor-channels in chronic pain pathways.Reduced spinal microglial activation and neuropathic pain after nerve injury in mice lacking all three nitric oxide synthases.Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic painMicroglia-neuronal signalling in neuropathic pain hypersensitivity 2.0.Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats.Role of P2X4 Receptor in Mouse Voiding Function.
P2860
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P2860
Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury
description
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Jahr 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/01/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/01/01)
@nl
наукова стаття, опублікована в січні 2008
@uk
مقالة علمية (نشرت عام 2008)
@ar
name
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@ast
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@en
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@nl
type
label
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@ast
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@en
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@nl
prefLabel
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@ast
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@en
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@nl
P2093
P356
P1433
P1476
Lyn tyrosine kinase is require ...... after peripheral nerve injury
@en
P2093
Emika Toyomitsu
Hidetoshi Tozaki-Saitoh
Kazuhide Inoue
Makoto Tsuda
Tadashi Yamamoto
Tohru Tezuka
P2860
P356
10.1002/GLIA.20591
P577
2008-01-01T00:00:00Z