A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1
about
The mechanism of μ-opioid receptor (MOR)-TRPV1 crosstalk in TRPV1 activation involves morphine anti-nociception, tolerance and dependenceTNFα induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to the plasmalemma via Munc18-1/syntaxin1/SNAP-25 mediated fusion.Networking with AKAPs: context-dependent regulation of anchored enzymesNerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to EpacSensitization of TRPA1 by Protein Kinase AThe cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel Functionβ-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel.AKAP150-mediated TRPV1 sensitization is disrupted by calcium/calmodulin.A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation.Laser modulation of heat and capsaicin receptor TRPV1 leads to thermal antinociception.The basal thermal sensitivity of the TRPV1 ion channel is determined by PKCβII.[EXPRESS] Epac and Nociceptor Sensitization.Epigenetic modification of DRG neuronal gene expression subsequent to nerve injury: etiological contribution to complex regional pain syndromes (Part II)Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia.PP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150.Peripheral group I metabotropic glutamate receptor activation leads to muscle mechanical hyperalgesia through TRPV1 phosphorylation in the rat.A synergistic effect of simultaneous TRPA1 and TRPV1 activations on vagal pulmonary C-fiber afferentsA-kinase anchoring protein 150 mediates transient receptor potential family V type 1 sensitivity to phosphatidylinositol-4,5-bisphosphateResolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1.Modality-specific mechanisms of protein kinase C-induced hypersensitivity of TRPV1: S800 is a polymodal sensitization site.Mice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophyPersistent Electrical Activity in Primary Nociceptors after Spinal Cord Injury Is Maintained by Scaffolded Adenylyl Cyclase and Protein Kinase A and Is Associated with Altered Adenylyl Cyclase Regulation.Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.P2X₃ and TRPV1 functionally interact and mediate sensitization of trigeminal sensory neurons.A-kinase anchoring protein 79/150 coordinates metabotropic glutamate receptor sensitization of peripheral sensory neurons.The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensorLoss of calcineurin in the spinal dorsal horn contributes to neuropathic pain, and intrathecal administration of the phosphatase provides prolonged analgesiaInduction of thermal and mechanical hypersensitivity by parathyroid hormone-related peptide through upregulation of TRPV1 function and trafficking.Roles of transient receptor potential channels in pain.Adenylyl cyclase--A-kinase anchoring protein complexes: the next dimension in cAMP signaling.A-kinase anchoring protein 150 controls protein kinase C-mediated phosphorylation and sensitization of TRPV1The transient receptor potential family of ion channelsCross-talk between calcium and protein kinase A in the regulation of cell migration.The thermo-TRP ion channel family: properties and therapeutic implications.Current perspectives on the modulation of thermo-TRP channels: new advances and therapeutic implications.Neurotrophins, endocannabinoids and thermo-transient receptor potential: a threesome in pain signalling.Molecular sensors and modulators of thermoreception.Modulation of nociceptive ion channels and receptors via protein-protein interactions: implications for pain relief.Ankyrin-rich membrane spanning protein as a novel modulator of transient receptor potential vanilloid 1-function in nociceptive neurons.AKAP-dependent sensitization of Ca(v) 3.2 channels via the EP(4) receptor/cAMP pathway mediates PGE(2) -induced mechanical hyperalgesia
P2860
Q26801420-009F6E5F-4E4B-4B5E-A10C-37298C24C7C3Q27348801-B6167CBA-6D9A-4E2F-82D7-F0410F6257A7Q28278715-582DC351-8A4E-483B-BE24-169F2BF934ECQ28581578-D84A71E3-E795-4CEF-A140-B68431DF1A8FQ28817508-00F4AA5D-C967-4819-A92D-CBC49BD24E17Q29147515-C31DF4DA-98AF-4A8C-9CF0-C3EC98410E7CQ30448011-BDDB809D-1B63-4F0B-B87D-949D8A08B47EQ30475148-55472765-7276-4BFF-854A-AD93FEE88789Q33686921-F060D869-8985-4422-A72A-98F93DABBC0FQ33714085-2E108187-C58C-4DCE-AD9D-573C398A76BFQ33735513-0ECA2B1F-E23B-42DD-8DE5-FEFBAC4C7D7BQ33866295-7EFF1387-6D09-4028-ABD0-AC0400C7E26BQ33933720-D5DA7A70-A492-4C01-A848-B578F90357C4Q34417678-6C5B27BF-C993-4199-8E83-C9888B0DAA6DQ34631957-7ABAD318-CEB8-45E1-B0D0-ADD63110976CQ34758481-1BE22356-C9AA-4678-8E97-A484EA379013Q35034872-8ABC6BBD-8C31-4115-8802-3B0BCC351D84Q35075369-822217C3-E75B-4626-9B65-CA14689ECDDAQ35452699-A0315AEE-A978-4479-8876-113FA0C8149AQ35472094-566D4D54-BCDA-4D26-AA2A-8A1908E54D28Q35577699-3DBACE76-8D39-407F-B3C9-1021D2555F2EQ36534368-9D2C9B1F-8979-4BDE-A30F-28992C5AC3CCQ36596179-C81386CA-F0DB-437D-A1FA-B61E02F9E64FQ36692631-B97EE97C-727F-4C1D-9ACA-7E01B27E21C3Q36751451-15EE8595-768F-4DC2-B9B4-6DC9B526B240Q37023861-3677F8CB-A370-4D4F-BDFB-81DBABD09359Q37185316-92CC79F2-D2CC-42D6-B453-6746672697DCQ37351505-A1092A43-EB3D-48CF-9781-DE12BFE4CD5EQ37388690-10C1BC20-533D-42EE-BA56-F11B0F09C5D3Q37415827-8A451727-1363-4C0D-8270-55730F7767F9Q37438112-2D8EA069-DF37-429B-A3A3-C38A9A652880Q37852820-2E854404-E806-4614-8A20-DDB19261417CQ37888270-4DC2F0DF-C9E5-4FC8-A29D-7D47CE5802B2Q37907351-18CEFE07-EDCB-475D-B7C0-C72F64038DE6Q37960107-C9F3AD54-1896-494F-81A7-A45D183277F8Q38185067-B2AB031D-71DF-421A-AE2D-F3019D31C726Q38418532-25B66F48-81B9-43D8-9D40-05B5C6750C61Q38514549-1586F016-944C-45A1-A519-86AA7FAB9C08Q38969880-FF12D229-CF42-4B23-A41D-B3F240ABBF28Q39290501-D50ABADA-46FA-4F31-A665-3F6C622A63DD
P2860
A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1
description
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im September 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/09/15)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/09/15)
@nl
наукова стаття, опублікована у вересні 2008
@uk
مقالة علمية (نشرت في 15-9-2008)
@ar
name
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@ast
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@en
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@nl
type
label
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@ast
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@en
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@nl
prefLabel
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@ast
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@en
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@nl
P2093
P2860
P1433
P1476
A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1
@en
P2093
Anibal Diogenes
Armen N. Akopian
Kenneth M. Hargreaves
Michael Henry
Nathaniel A. Jeske
Nikita B. Ruparel
P2860
P304
P356
10.1016/J.PAIN.2008.02.022
P407
P577
2008-09-15T00:00:00Z