A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1 - sprookjes - yvandenbroek - TriplyDB

A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1

A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1

http://www.wikidata.org/entity/Q28568896

about

The mechanism of μ-opioid receptor (MOR)-TRPV1 crosstalk in TRPV1 activation involves morphine anti-nociception, tolerance and dependence TNFα induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to the plasmalemma via Munc18-1/syntaxin1/SNAP-25 mediated fusion.Networking with AKAPs: context-dependent regulation of anchored enzymes Nerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to Epac Sensitization of TRPA1 by Protein Kinase A The cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel Function β-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel.AKAP150-mediated TRPV1 sensitization is disrupted by calcium/calmodulin.A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation.Laser modulation of heat and capsaicin receptor TRPV1 leads to thermal antinociception.The basal thermal sensitivity of the TRPV1 ion channel is determined by PKCβII.[EXPRESS] Epac and Nociceptor Sensitization.Epigenetic modification of DRG neuronal gene expression subsequent to nerve injury: etiological contribution to complex regional pain syndromes (Part II)Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia.PP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150.Peripheral group I metabotropic glutamate receptor activation leads to muscle mechanical hyperalgesia through TRPV1 phosphorylation in the rat.A synergistic effect of simultaneous TRPA1 and TRPV1 activations on vagal pulmonary C-fiber afferents A-kinase anchoring protein 150 mediates transient receptor potential family V type 1 sensitivity to phosphatidylinositol-4,5-bisphosphate Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1.Modality-specific mechanisms of protein kinase C-induced hypersensitivity of TRPV1: S800 is a polymodal sensitization site.Mice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophy Persistent Electrical Activity in Primary Nociceptors after Spinal Cord Injury Is Maintained by Scaffolded Adenylyl Cyclase and Protein Kinase A and Is Associated with Altered Adenylyl Cyclase Regulation.Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.P2X₃ and TRPV1 functionally interact and mediate sensitization of trigeminal sensory neurons.A-kinase anchoring protein 79/150 coordinates metabotropic glutamate receptor sensitization of peripheral sensory neurons.The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor Loss of calcineurin in the spinal dorsal horn contributes to neuropathic pain, and intrathecal administration of the phosphatase provides prolonged analgesia Induction of thermal and mechanical hypersensitivity by parathyroid hormone-related peptide through upregulation of TRPV1 function and trafficking.Roles of transient receptor potential channels in pain.Adenylyl cyclase--A-kinase anchoring protein complexes: the next dimension in cAMP signaling.A-kinase anchoring protein 150 controls protein kinase C-mediated phosphorylation and sensitization of TRPV1 The transient receptor potential family of ion channels Cross-talk between calcium and protein kinase A in the regulation of cell migration.The thermo-TRP ion channel family: properties and therapeutic implications.Current perspectives on the modulation of thermo-TRP channels: new advances and therapeutic implications.Neurotrophins, endocannabinoids and thermo-transient receptor potential: a threesome in pain signalling.Molecular sensors and modulators of thermoreception.Modulation of nociceptive ion channels and receptors via protein-protein interactions: implications for pain relief.Ankyrin-rich membrane spanning protein as a novel modulator of transient receptor potential vanilloid 1-function in nociceptive neurons.AKAP-dependent sensitization of Ca(v) 3.2 channels via the EP(4) receptor/cAMP pathway mediates PGE(2) -induced mechanical hyperalgesia

P2860

Q26801420-009F6E5F-4E4B-4B5E-A10C-37298C24C7C3 Q27348801-B6167CBA-6D9A-4E2F-82D7-F0410F6257A7 Q28278715-582DC351-8A4E-483B-BE24-169F2BF934EC Q28581578-D84A71E3-E795-4CEF-A140-B68431DF1A8F Q28817508-00F4AA5D-C967-4819-A92D-CBC49BD24E17 Q29147515-C31DF4DA-98AF-4A8C-9CF0-C3EC98410E7C Q30448011-BDDB809D-1B63-4F0B-B87D-949D8A08B47E Q30475148-55472765-7276-4BFF-854A-AD93FEE88789 Q33686921-F060D869-8985-4422-A72A-98F93DABBC0F Q33714085-2E108187-C58C-4DCE-AD9D-573C398A76BF Q33735513-0ECA2B1F-E23B-42DD-8DE5-FEFBAC4C7D7B Q33866295-7EFF1387-6D09-4028-ABD0-AC0400C7E26B Q33933720-D5DA7A70-A492-4C01-A848-B578F90357C4 Q34417678-6C5B27BF-C993-4199-8E83-C9888B0DAA6D Q34631957-7ABAD318-CEB8-45E1-B0D0-ADD63110976C Q34758481-1BE22356-C9AA-4678-8E97-A484EA379013 Q35034872-8ABC6BBD-8C31-4115-8802-3B0BCC351D84 Q35075369-822217C3-E75B-4626-9B65-CA14689ECDDA Q35452699-A0315AEE-A978-4479-8876-113FA0C8149A Q35472094-566D4D54-BCDA-4D26-AA2A-8A1908E54D28 Q35577699-3DBACE76-8D39-407F-B3C9-1021D2555F2E Q36534368-9D2C9B1F-8979-4BDE-A30F-28992C5AC3CC Q36596179-C81386CA-F0DB-437D-A1FA-B61E02F9E64F Q36692631-B97EE97C-727F-4C1D-9ACA-7E01B27E21C3 Q36751451-15EE8595-768F-4DC2-B9B4-6DC9B526B240 Q37023861-3677F8CB-A370-4D4F-BDFB-81DBABD09359 Q37185316-92CC79F2-D2CC-42D6-B453-6746672697DC Q37351505-A1092A43-EB3D-48CF-9781-DE12BFE4CD5E Q37388690-10C1BC20-533D-42EE-BA56-F11B0F09C5D3 Q37415827-8A451727-1363-4C0D-8270-55730F7767F9 Q37438112-2D8EA069-DF37-429B-A3A3-C38A9A652880 Q37852820-2E854404-E806-4614-8A20-DDB19261417C Q37888270-4DC2F0DF-C9E5-4FC8-A29D-7D47CE5802B2 Q37907351-18CEFE07-EDCB-475D-B7C0-C72F64038DE6 Q37960107-C9F3AD54-1896-494F-81A7-A45D183277F8 Q38185067-B2AB031D-71DF-421A-AE2D-F3019D31C726 Q38418532-25B66F48-81B9-43D8-9D40-05B5C6750C61 Q38514549-1586F016-944C-45A1-A519-86AA7FAB9C08 Q38969880-FF12D229-CF42-4B23-A41D-B3F240ABBF28 Q39290501-D50ABADA-46FA-4F31-A665-3F6C622A63DD

P2860

A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1

http://www.wikidata.org/entity/Q28568896

description

2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2008

@ast

im September 2008 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2008/09/15)

@sk

vědecký článek publikovaný v roce 2008

@cs

wetenschappelijk artikel (gepubliceerd op 2008/09/15)

@nl

наукова стаття, опублікована у вересні 2008

@uk

مقالة علمية (نشرت في 15-9-2008)

@ar

name

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@ast

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@en

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@nl

type

label

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@ast

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@en

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@nl

prefLabel

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@ast

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@en

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@nl

P1433

Q28568896-318484A6-8D64-4E68-AB98-5F9C5FF8A2C0

P1476

Q28568896-5DB798FD-77C6-4AE2-8BEA-BDFDC92745BD

P2093

Q28568896-07B6E5D6-32A3-478C-9C35-CB322A9934EE

Q28568896-0FDBAC1C-D899-46BE-8274-BBE9B1F4A6E7

Q28568896-2ABB9183-8566-4FCD-AB9D-74B638BD17D4

Q28568896-83DCA556-A14D-4C49-A903-970A0EFFB968

Q28568896-B654E157-BCB2-4677-BE3D-A311F3A2F760

Q28568896-EA65A098-C120-46F9-B46F-020F2D49D14C

P2860

Q28568896-060C4041-F837-40A7-B88A-068DFAAA9DA1

Q28568896-0AEFCF70-F18B-4C36-AF52-91661C34BD1F

Q28568896-0C949612-67C1-4E46-B20E-C382C4AA3D8F

Q28568896-15034FCB-D4FE-4D06-8C57-E3227E265F35

Q28568896-1BF2B18B-14AC-4E20-A685-1DC4D99AD037

Q28568896-252CA6EC-1A09-4BA9-A109-60088C0055E6

Q28568896-2CA98B28-6708-48AF-8FA3-6A36EA16880A

Q28568896-2E31E7C3-BE43-441D-9942-59821BFFCC72

Q28568896-314EC15B-719B-4F55-B2E8-9AE1C5AB4161

Q28568896-39323CF2-5061-4FD2-9D51-C0265BE96C39

P304

Q28568896-62297DA9-35A8-4E6F-9F77-65673B428CD3

P31

Q28568896-3E47E790-FF25-4822-AEFC-C61D6A5AC41B

P356

Q28568896-F3CC9F4A-4351-4DAB-8877-20C8262D4045

P407

Q28568896-DAAB4479-8BB9-40F4-BFCF-0C765148042D

P433

Q28568896-420AEA1D-B4BE-4600-B445-A27EF99F9D58

P478

Q28568896-DA5093B9-9FD9-45E4-AAE9-5FDEAF984047

P50

Q28568896-3C079BC2-A71D-43CE-9EE8-21B61A089D46

P577

Q28568896-13DA70D7-7934-4284-90CD-701967D694AB

P5875

Q28568896-3598B660-1C09-4BA4-BE9F-E9197514E389

P698

Q28568896-D34BB34B-B286-4DFC-AFBD-B35B28E0DE1B

P921

Q28568896-4D76D6F9-436A-42A3-9109-F280EEF15E71

P932

Q28568896-B3C7AD1B-7AB3-4114-A635-B01AB29437CB

P356

J.PAIN.2008.02.022

P1433

P1476

A-kinase anchoring protein med ...... h PKA phosphorylation of TRPV1

@en

P2093

Anibal Diogenes

http://www.w3.org/2001/XMLSchema#string

Armen N. Akopian

http://www.w3.org/2001/XMLSchema#string

Kenneth M. Hargreaves

http://www.w3.org/2001/XMLSchema#string

Michael Henry

http://www.w3.org/2001/XMLSchema#string

Nathaniel A. Jeske

http://www.w3.org/2001/XMLSchema#string

Nikita B. Ruparel

http://www.w3.org/2001/XMLSchema#string

P2860

A capsaicin-receptor homologue with a high threshold for noxious heat

Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Ion channels gated by heat

Structural determinant of TRPV1 desensitization interacts with calmodulin

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex

A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta

P304

604–616

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.PAIN.2008.02.022

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

138

http://www.w3.org/2001/XMLSchema#string

P50

Jill C. Fehrenbacher

P577

2008-09-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5471898

http://www.w3.org/2001/XMLSchema#string

P698

18381233

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

2593399

http://www.w3.org/2001/XMLSchema#string