Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils
about
GSK-3 Inhibitors: Preclinical and Clinical Focus on CNSMutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathwaysTherapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorderThe links between axin and carcinogenesisGlycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeuticsMolecular Mechanism of Adult Neurogenesis and its Association with Human Brain DiseasesTargeting the Wnt pathways for therapiesThe dynamic role of beta-catenin in synaptic plasticityWnts in action: from synapse formation to synaptic maintenanceSignalled roads to memory and its degenerationUncovering novel actors in astrocyte-neuron crosstalk in Parkinson's disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repairAmyloid beta: multiple mechanisms of toxicity and only some protective effects?Is L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type miceCellular plasticity cascades in the pathophysiology and treatment of bipolar disorderThe ups and downs of Wnt signaling in prevalent neurological disordersA Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotectionWNT and beta-catenin signalling: diseases and therapiesGlycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithiumUncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 miceA systematic review of existing data on long-term lithium therapy: neuroprotective or neurotoxic?The excitotoxin quinolinic acid induces tau phosphorylation in human neuronsThe neurotrophic and neuroprotective effects of psychotropic agents.A common biological mechanism in cancer and Alzheimer's disease?Lithium enhances axonal regeneration in peripheral nerve by inhibiting glycogen synthase kinase 3β activation.Lithium ameliorates autistic-like behaviors induced by neonatal isolation in rats.WNT5A signaling contributes to Aβ-induced neuroinflammation and neurotoxicity.Huperzine A: Is it an Effective Disease-Modifying Drug for Alzheimer's Disease?Differential expression of Wnts after spinal cord contusion injury in adult rats.Wnt1 neuroprotection translates into improved neurological function during oxidant stress and cerebral ischemia through AKT1 and mitochondrial apoptotic pathways.Lack of evidence of the interaction of the Aβ peptide with the Wnt signaling cascade in Drosophila models of Alzheimer's diseaseEnhancing Beta-Catenin Activity via GSK3beta Inhibition Protects PC12 Cells against Rotenone Toxicity through Nurr1 Induction.Hyperforin prevents beta-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer's amyloid-beta-deposits.WNT signaling in activated microglia is proinflammatory.Huperzine A activates Wnt/β-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse modelThe amyloid beta ion channel hypothesis of Alzheimer's disease.The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways.In vivo regulation of GSK3 phosphorylation by cholinergic and NMDA receptors.Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disordersNeuroprotective action of lithium in disorders of the central nervous system.
P2860
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P2860
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils
description
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Februar 2003 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2003/02/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/02/01)
@nl
наукова стаття, опублікована в лютому 2003
@uk
مقالة علمية (نشرت في فبراير 2003)
@ar
name
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@ast
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@en
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@nl
type
label
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@ast
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@en
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@nl
prefLabel
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@ast
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@en
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@nl
P2093
P2860
P3181
P356
P1433
P1476
Activation of Wnt signaling re ...... nduced by beta-amyloid fibrils
@en
P2093
Bronfman M
Garrido JL
Inestrosa NC
Olivares G
P2860
P2888
P304
P3181
P356
10.1038/SJ.MP.4001208
P407
P577
2003-02-01T00:00:00Z