Nedd4-2 induces endocytosis and degradation of proteolytically cleaved epithelial Na+ channels
about
Regulation of epithelial sodium channel trafficking by proprotein convertase subtilisin/kexin type 9 (PCSK9)Epithelial Na(+) channel regulation by cytoplasmic and extracellular factorsUbiquitylation and control of renal Na+ balance and blood pressureDeletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like diseaseNedd4-2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epitheliaDelivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis.Cholera toxin enhances Na(+) absorption across MCF10A human mammary epithelia.Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes.Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2.Regulation of sodium transport by ENaC in the kidneyPhosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel.Epithelial Na+ channel (ENaC), hormones, and hypertension.Regulation of the epithelial sodium channel (ENaC) by membrane traffickingUnique regulation of human Na+/H+ exchanger 3 (NHE3) by Nedd4-2 ligase that differs from non-primate NHE3s.Hrs controls sorting of the epithelial Na+ channel between endosomal degradation and recycling pathwaysThe epithelial sodium channel (ENaC) establishes a trafficking vesicle pool responsible for its regulationCollecting duct principal cell transport processes and their regulation.Nedd4-mediated AMPA receptor ubiquitination regulates receptor turnover and trafficking.Saccharomyces cerivisiae as a model system for kidney disease: what can yeast tell us about renal function?H-Ras mediates the inhibitory effect of epidermal growth factor on the epithelial Na+ channelNeural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites.Acetylation stimulates the epithelial sodium channel by reducing its ubiquitination and degradationRab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC).Regulation of transport in the connecting tubule and cortical collecting ductUbiquitin-specific peptidase 8 (USP8) regulates endosomal trafficking of the epithelial Na+ channelH2O2 regulates lung epithelial sodium channel (ENaC) via ubiquitin-like protein Nedd8.Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells.WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitinationRegulation of the epithelial sodium channel by membrane trafficking.A new SGK1 knockout mouse.The activity of the epithelial sodium channels is regulated by caveolin-1 via a Nedd4-2-dependent mechanism.Hsc70 negatively regulates epithelial sodium channel trafficking at multiple sites in epithelial cells.Some assembly required: putting the epithelial sodium channel together.Anterograde transport of surfactant protein C proprotein to distal processing compartments requires PPDY-mediated association with Nedd4 ubiquitin ligasesENaC at the cutting edge: regulation of epithelial sodium channels by proteases.AF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel alpha.Alternative mechanism of activation of the epithelial na+ channel by cleavage.ENaC activity is increased in isolated, split-open cortical collecting ducts from protein kinase Cα knockout mice.Molecular physiology of the medullary collecting duct.Interactions of U24 from Roseolovirus with WW domains: canonical vs noncanonical.
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P2860
Nedd4-2 induces endocytosis and degradation of proteolytically cleaved epithelial Na+ channels
description
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2008
@ast
im März 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/03/07)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/03/07)
@nl
наукова стаття, опублікована в березні 2008
@uk
name
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
@ast
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
@en
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
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type
label
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
@ast
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
@en
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
@nl
prefLabel
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
@ast
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
@en
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
@nl
P2093
P2860
P356
P1476
Nedd4-2 induces endocytosis an ...... leaved epithelial Na+ channels
@en
P2093
Kristin K. Knight
Peter M. Snyder
Rajesh Kabra
Ruifeng Zhou
P2860
P304
P356
10.1074/JBC.M708555200
P407
P577
2008-03-07T00:00:00Z