ANG II promotes IGF-IIR expression and cardiomyocyte apoptosis by inhibiting HSF1 via JNK activation and SIRT1 degradation
about
Sirtuins in epigenetic regulationSIRT1 functions as an important regulator of estrogen-mediated cardiomyocyte protection in angiotensin II-induced heart hypertrophy.Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer.Anthocyanin Attenuates Doxorubicin-Induced Cardiomyotoxicity via Estrogen Receptor-α/β and Stabilizes HSF1 to Inhibit the IGF-IIR Apoptotic Pathway.Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts.Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death.Molecular switches under TGFβ signalling during progression from cardiac hypertrophy to heart failure.Signaling Pathways in Cardiac Myocyte Apoptosis.p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure.Tanshinone IIA Inhibits β-Catenin Nuclear Translocation and IGF-2R Activation via Estrogen Receptors to Suppress Angiotensin II-Induced H9c2 Cardiomyoblast Cell Apoptosis.Mitochondrial ROS-induced ERK1/2 activation and HSF2-mediated AT1 R upregulation are required for doxorubicin-induced cardiotoxicity.Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure.Exacerbation of diabetic cardiac hypertrophy in OVE26 mice by angiotensin II is associated with JNK/c-Jun/miR-221-mediated autophagy inhibition.Tanshinone-induced ERs suppresses IGFII activation to alleviate Ang II-mediated cardiac hypertrophy.Short-term hypoxia upregulated Mas receptor expression to repress the AT1 R signaling pathway and attenuate Ang II-induced cardiomyocyte apoptosis.HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF-IIR expression for hypertension-induced cardiomyocyte hypertrophy.Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway.Sirtuins in the Cardiovascular System: Potential Targets in Pediatric Cardiology.Anti-Apoptosis and Anti-Fibrosis Effects of Eriobotrya Japonica in Spontaneously Hypertensive Rat Hearts.Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway
P2860
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P2860
ANG II promotes IGF-IIR expression and cardiomyocyte apoptosis by inhibiting HSF1 via JNK activation and SIRT1 degradation
description
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2014
@ast
im August 2014 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2014/08/01)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/08/01)
@nl
наукова стаття, опублікована в серпні 2014
@uk
مقالة علمية (نشرت في أغسطس 2014)
@ar
name
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@ast
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@en
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@nl
type
label
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@ast
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@en
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@nl
prefLabel
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@ast
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@en
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@nl
P2093
P2860
P3181
P356
P1476
ANG II promotes IGF-IIR expres ...... tivation and SIRT1 degradation
@en
P2093
C.-H. Tsai
C.-Y. Huang
F.-J. Tsai
P2860
P2888
P304
P3181
P356
10.1038/CDD.2014.46
P577
2014-08-01T00:00:00Z