Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
about
Insulin in central nervous system: more than just a peripheral hormoneNaturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanismIntranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidenceBrain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in HumansOne for All? Hitting Multiple Alzheimer's Disease Targets with One DrugInflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's DiseaseAlzheimer's Disease: Mechanism and Approach to Cell TherapyInsulin: an emerging treatment for Alzheimer's disease dementia?Link between type 2 diabetes and Alzheimer's disease: from epidemiology to mechanism and treatmentThe impairment of insulin signaling in Alzheimer's diseaseNew drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseasesAlzheimer's disease and insulin resistance: translating basic science into clinical applicationsElevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brainNew cellular and molecular approaches to ageing brainInsulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndromeBrain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogsDiabetes and Alzheimer disease, two overlapping pathologies with the same background: oxidative stressAberrant insulin signaling in Alzheimer's disease: current knowledgeChronic adjunction of 1-deoxynojirimycin protects from age-related behavioral and biochemical changes in the SAMP8 mice.High-fat diet impairs spatial memory and hippocampal intrinsic excitability and sex-dependently alters circulating insulin and hippocampal insulin sensitivityNovel microRNAs differentially expressed during aging in the mouse brainA blood based 12-miRNA signature of Alzheimer disease patientsThe dendritic hypothesis for Alzheimer's disease pathophysiology.Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomersTranscriptome sequencing of gene expression in the brain of the HIV-1 transgenic rat.Bridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive PotentialProtection against the synaptic targeting and toxicity of Alzheimer's-associated Aβ oligomers by insulin mimetic chiro-inositols.Insulin-induced generation of reactive oxygen species and uncoupling of nitric oxide synthase underlie the cerebrovascular insulin resistance in obese rats.Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease.The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin.Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy.The nature, significance, and glucagon-like peptide-1 analog treatment of brain insulin resistance in Alzheimer's disease.Cerebrovascular responses to insulin in rats.Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer's Disease.Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice.Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.Repurposing diabetes drugs for brain insulin resistance in Alzheimer disease.Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors.Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early InterventionRecruiting adaptive cellular stress responses for successful brain ageing.
P2860
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P2860
Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
description
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Februar 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/02/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/02/01)
@nl
наукова стаття, опублікована в лютому 2010
@uk
مقالة علمية (نشرت في فبراير 2010)
@ar
name
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@ast
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@en
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@nl
type
label
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@ast
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@en
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@nl
prefLabel
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@ast
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@en
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@nl
P2093
P50
P3181
P1476
Defects in IGF-1 receptor, ins ...... o IGF-1 and insulin signalling
@en
P2093
Aileen M Moloney
Rebecca J Griffin
Rivka Ravid
P304
P3181
P356
10.1016/J.NEUROBIOLAGING.2008.04.002
P577
2010-02-01T00:00:00Z