A conserved aspartate (Asp-1393) regulates NADPH reduction of neuronal nitric-oxide synthase: implications for catalysis
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NO formation by neuronal NO-synthase can be controlled by ultrafast electron injection from a nanotrigger.Regulation of interdomain electron transfer in the NOS output state for NO productionMechanism of Nitric Oxide Synthase Regulation: Electron Transfer and Interdomain Interactions.Solving Kinetic Equations for the Laser Flash Photolysis Experiment on Nitric Oxide Synthases: Effect of Conformational Dynamics on the Interdomain Electron Transfer.Depletion of NADP(H) due to CD38 activation triggers endothelial dysfunction in the postischemic heart.Control of electron transfer and catalysis in neuronal nitric-oxide synthase (nNOS) by a hinge connecting its FMN and FAD-NADPH domains.Neutralizing a surface charge on the FMN subdomain increases the activity of neuronal nitric-oxide synthase by enhancing the oxygen reactivity of the enzyme heme-nitric oxide complexDissecting regulation mechanism of the FMN to heme interdomain electron transfer in nitric oxide synthases.Towards the free energy landscape for catalysis in mammalian nitric oxide synthases.Transcriptome atlas of glutamine family amino acid metabolism-related genes in eight regenerating liver cell types.Intracellular location regulates calcium-calmodulin-dependent activation of organelle-restricted eNOS.C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase.Restricting the conformational freedom of the neuronal nitric-oxide synthase flavoprotein domain reveals impact on electron transfer and catalysis.
P2860
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P2860
A conserved aspartate (Asp-1393) regulates NADPH reduction of neuronal nitric-oxide synthase: implications for catalysis
description
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im April 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/04/30)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/04/30)
@nl
наукова стаття, опублікована у квітні 2004
@uk
name
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@ast
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@en
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@nl
type
label
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@ast
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@en
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@nl
prefLabel
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@ast
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@en
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@nl
P2093
P2860
P356
P1476
A conserved aspartate (Asp-139 ...... se: implications for catalysis
@en
P2093
David Konas
Dennis J Stuehr
Manisha Sharma
Subrata Adak
P2860
P304
18323-18333
P356
10.1074/JBC.M310391200
P407
P577
2004-02-13T00:00:00Z