Tanshinone II A down-regulates HMGB1, RAGE, TLR4, NF-kappaB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia
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Acacetin inhibits glutamate release and prevents kainic acid-induced neurotoxicity in ratsSodium Tanshinone IIA Sulfonate Enhances Effectiveness Rt-PA Treatment in Acute Ischemic Stroke Patients Associated with Ameliorating Blood-Brain Barrier Damage.Protective effect of tanshinone IIA on the brain and its therapeutic time window in rat models of cerebral ischemia-reperfusionAmitriptyline up-regulates connexin43-gap junction in rat cultured cortical astrocytes via activation of the p38 and c-Fos/AP-1 signalling pathwayHMGB1 in health and disease.Claudins and the modulation of tight junction permeability.Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptakePrevention and Therapeutic Effects and Mechanisms of Tanshinone IIA Sodium Sulfonate on Acute Liver Injury Mice Model.Emerging role of high-mobility group box 1 (HMGB1) in liver diseases.One-Compound-Multi-Target: Combination Prospect of Natural Compounds with Thrombolytic Therapy in Acute Ischemic Stroke.The Immunomodulatory Effects of Plant Extracts and Plant Secondary Metabolites on Chronic Neuroinflammation and Cognitive Aging: A Mechanistic and Empirical Review.Non-histone nuclear factor HMGB1 as a therapeutic target in colorectal cancer.Identification of circulating microRNAs as potential biomarkers for detecting acute ischemic stroke.Salvianolic Acids Enhance Cerebral Angiogenesis and Neurological Recovery by Activating JAK2/STAT3 Signaling Pathway after Ischemic Stroke in Mice.Tanshinone IIA inhibits lipopolysaccharide-induced MUC1 overexpression in alveolar epithelial cells.Sterile Neuroinflammation and Strategies for Therapeutic InterventionTanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL-6/STAT3/NF-kB signaling pathways.Potential medications or compounds acting on toll-like receptors in cerebral ischemia.Protective Effect of Aliskiren in Experimental Ischemic Stroke: Up-Regulated p-PI3K, p-AKT, Bcl-2 Expression, Attenuated Bax Expression.Preconditioned hyperbaric oxygenation protects skin flap grafts in rats against ischemia/reperfusion injury.Ferulic acid exerts neuroprotective effects against cerebral ischemia/reperfusion-induced injury via antioxidant and anti-apoptotic mechanisms in vitro and in vivo.Pretreatment by evodiamine is neuroprotective in cerebral ischemia: up-regulated pAkt, pGSK3β, down-regulated NF-κB expression, and ameliorated BBB permeability.Parthenolide is neuroprotective in rat experimental stroke model: downregulating NF-κB, phospho-p38MAPK, and caspase-1 and ameliorating BBB permeability.Protective effect of shikonin in experimental ischemic stroke: attenuated TLR4, p-p38MAPK, NF-κB, TNF-α and MMP-9 expression, up-regulated claudin-5 expression, ameliorated BBB permeability.Protective effect of Tanshinone IIA against infarct size and increased HMGB1, NFκB, GFAP and apoptosis consequent to transient middle cerebral artery occlusion.Reducing effect of IL-32α in the development of stroke through blocking of NF-κB, but enhancement of STAT3 pathways.Anti-epileptic effect of ifenprodil on neocortical pyramidal neurons in patients with malformations of cortical development.Hexahydrocurcumin protects against cerebral ischemia/reperfusion injury, attenuates inflammation, and improves antioxidant defenses in a rat stroke model.Pivotal neuroinflammatory and therapeutic role of high mobility group box 1 in ischemic stroke.Suppression of TLR4/NF-κB Signaling Pathway Improves Cerebral Ischemia-Reperfusion Injury in Rats.Association of GWAS-Supported Variants rs556621 on Chromosome 6p21.1 with Large Artery Atherosclerotic Stroke in a Southern Chinese Han Population.Ulinastatin downregulates TLR4 and NF-kB expression and protects mouse brains against ischemia/reperfusion injury.Neuroprotective effects of rhynchophylline against ischemic brain injury via regulation of the Akt/mTOR and TLRs signaling pathways.Glycyrrhizin protects spinal cord and reduces inflammation in spinal cord ischemia-reperfusion injury.Protective effect of naringenin in experimental ischemic stroke: down-regulated NOD2, RIP2, NF-κB, MMP-9 and up-regulated claudin-5 expression.
P2860
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P2860
Tanshinone II A down-regulates HMGB1, RAGE, TLR4, NF-kappaB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia
description
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im März 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/03/19)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/03/19)
@nl
наукова стаття, опублікована в березні 2010
@uk
مقالة علمية نشرت في 19-3-2010 حول موضوع: دماغ
@ar
name
Tanshinone II A down-regulates ...... brains against focal ischemia
@ast
Tanshinone II A down-regulates ...... brains against focal ischemia
@en
Tanshinone II A down-regulates ...... brains against focal ischemia
@nl
type
label
Tanshinone II A down-regulates ...... brains against focal ischemia
@ast
Tanshinone II A down-regulates ...... brains against focal ischemia
@en
Tanshinone II A down-regulates ...... brains against focal ischemia
@nl
prefLabel
Tanshinone II A down-regulates ...... brains against focal ischemia
@ast
Tanshinone II A down-regulates ...... brains against focal ischemia
@en
Tanshinone II A down-regulates ...... brains against focal ischemia
@nl
P2093
P921
P3181
P1433
P1476
Tanshinone II A down-regulates ...... brains against focal ischemia
@en
P2093
Lingling Liu
Xiangjian Zhang
P304
P3181
P356
10.1016/J.BRAINRES.2009.12.046
P407
P577
2010-03-19T00:00:00Z