Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
about
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retinaEthanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to alpha4/6beta3delta GABAA receptorsLocalization of the gene encoding the GABAA receptor beta 3 subunit to the Angelman/Prader-Willi region of human chromosome 15Genetic mapping of the beta 1 GABA receptor gene to human chromosome 4, using a tetranucleotide repeat polymorphismGABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.Potentiation of Gamma Aminobutyric Acid Receptors (GABAAR) by Ethanol: How Are Inhibitory Receptors Affected?The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channelsEffects of GABA(A) receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositionsTargeted disruption of the GABA(A) receptor delta subunit gene leads to an up-regulation of gamma 2 subunit-containing receptors in cerebellar granule cellsThe third gamma subunit of the gamma-aminobutyric acid type A receptor familyA Tribute to Peter H Seeburg (1944-2016): A Founding Father of Molecular Neurobiology.Cerebellar and extracerebellar involvement in mouse eyeblink conditioning: the ACDC model.Human breast cancer metastases to the brain display GABAergic properties in the neural niche.Early expression of GABA(A) receptor delta subunit in the neonatal rat hippocampus.Five subtypes of type A gamma-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies.Pharmacological Properties of DOV 315,090, an ocinaplon metabolite.Neurologic effects of alcoholismHooked on benzodiazepines: GABAA receptor subtypes and addiction.Increased A-to-I RNA editing of the transcript for GABAA receptor subunit α3 during chick retinal development.Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors.New insights into the mechanism of action of hypnotics.Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site.Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels.Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor.Reduced effect of NMDA glutamate receptor antagonist on ethanol-induced ataxia and striatal glutamate levels in mice lacking ENT1.Positioning of the alpha-subunit isoforms confers a functional signature to gamma-aminobutyric acid type A receptors.Ethanol, gamma-aminobutyrate type A receptors, and protein kinase C phosphorylation.Processing of multi-dimensional sensorimotor information in the spinal and cerebellar neuronal circuitry: a new hypothesis.Trichloroethanol potentiation of gamma-aminobutyric acid-activated chloride current in mouse hippocampal neurones.Immunization against GAD induces antibody binding to GAD-independent antigens and brainstem GABAergic neuronal lossAntagonistic action of pitrazepin on human and rat GABA(A) receptors.NMDA receptors: role in ethanol withdrawal seizures.Changes in gamma-aminobutyrate type A receptor subunit mRNAs, translation product expression, and receptor function during neuronal maturation in vitro.GABAergic signaling in the developing cerebellum.Sequence of a functional invertebrate GABAA receptor subunit which can form a chimeric receptor with a vertebrate alpha subunit.Quantification of the synaptosomal proteome of the rat cerebellum during post-natal development.Tonic for what ails us? high-affinity GABAA receptors and alcoholDifferential affinity of dihydroimidazoquinoxalines and diimidazoquinazolines to the alpha 1 beta 2 gamma 2 and alpha 6 beta 2 gamma 2 subtypes of cloned GABAA receptorsDirecting gene expression to cerebellar granule cells using gamma-aminobutyric acid type A receptor alpha6 subunit transgenes.Respiratory and behavioral dysfunction following loss of the GABAA receptor α4 subunit.
P2860
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P2860
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
description
1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 1990
@ast
scientific journal article
@en
vedecký článok (publikovaný 1990/08/16)
@sk
vědecký článek publikovaný v roce 1990
@cs
wetenschappelijk artikel (gepubliceerd op 1990/08/16)
@nl
наукова стаття, опублікована в серпні 1990
@uk
مقالة علمية (نشرت في 16-8-1990)
@ar
name
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@ast
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@en
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@nl
type
label
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@ast
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@en
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@nl
prefLabel
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@ast
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@en
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@nl
P2093
P50
P3181
P356
P1433
P1476
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist
@en
P2093
D. B. Pritchett
H. Lüddens
I. Killisch
K. Keinänen
P2888
P304
P3181
P356
10.1038/346648A0
P407
P577
1990-08-16T00:00:00Z
P6179
1031769666