A chloride channel widely expressed in epithelial and non-epithelial cells
about
ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytesTwo highly homologous members of the ClC chloride channel family in both rat and human kidneyAlternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specificIdiopathic low molecular weight proteinuria associated with hypercalciuric nephrocalcinosis in Japanese children is due to mutations of the renal chloride channel (CLCN5)Multimeric structure of ClC-1 chloride channel revealed by mutations in dominant myotonia congenita (Thomsen)Molecular basis for decreased muscle chloride conductance in the myotonic goatChloride channels as drug targets.Diversity of Cl(-) channelsSpectrum of mutations in the major human skeletal muscle chloride channel gene (CLCN1) leading to myotoniaNovel muscle chloride channel mutations and their effects on heterozygous carriersThe functioning of mammalian ClC-2 chloride channel in Saccharomyces cerevisiae cells requires an increased level of Kha1pClC-2 regulation of intestinal barrier function: Translation of basic science to therapeutic targetDiscovery of CLC transport proteins: cloning, structure, function and pathophysiologyAnion transport in heartFundamental role of ClC-3 in volume-sensitive Cl- channel function and cell volume regulation in AGS cellsDistribution of ClC-2 chloride channel in rat and human epithelial tissuesEvidence for a functional interaction between the ClC-2 chloride channel and the retrograde motor dynein complexOntogeny of CLCN3 chloride channel gene expression in human pulmonary epitheliumLoss of hyperpolarization-activated Cl(-) current in salivary acinar cells from Clcn2 knockout miceSites of protein kinase A activation of the human ClC-2 Cl(-) channelAssociation between Hsp90 and the ClC-2 chloride channel upregulates channel functionFunctional evaluation of human ClC-2 chloride channel mutations associated with idiopathic generalized epilepsiesIs the ClC-2 chloride channel involved in the Cl- secretory mechanism of gastric parietal cells?Chloride channels: an emerging molecular pictureModulation of the gating of CIC-1 by S-(-) 2-(4-chlorophenoxy) propionic acidExpression of volume-sensitive Cl(-) channels and ClC-3 in acinar cells isolated from the rat lacrimal gland and submandibular salivary glandA pH-sensitive chloride current in the chemoreceptor cell of rat carotid bodyMale germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruptionDCPIB is a novel selective blocker of I(Cl,swell) and prevents swelling-induced shortening of guinea-pig atrial action potential durationInhibition of CLC-2 chloride channel expression interrupts expansion of fetal lung cystsLubiprostone stimulates duodenal bicarbonate secretion in ratsLocalization and functional characterization of rat kidney-specific chloride channel, ClC-K1A Novel voltage-dependent chloride current activated by extracellular acidic pH in cultured rat Sertoli cellsAbsence of the skeletal muscle sarcolemma chloride channel ClC-1 in myotonic miceHyperpolarization-activated chloride currents in Xenopus oocytes.Inward-rectifier chloride currents in Reissner's membrane epithelial cellsBasolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1.Inward-rectifying anion channels are expressed in the epithelial cells of choroid plexus isolated from ClC-2 'knock-out' mice.Splice variants of a ClC-2 chloride channel with differing functional characteristics.Autism-epilepsy phenotype with macrocephaly suggests PTEN, but not GLIALCAM, genetic screening.
P2860
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P2860
A chloride channel widely expressed in epithelial and non-epithelial cells
description
1992 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 1992
@ast
scientific journal article
@en
vedecký článok (publikovaný 1992/03/05)
@sk
vědecký článek publikovaný v roce 1992
@cs
wetenschappelijk artikel (gepubliceerd op 1992/03/05)
@nl
наукова стаття, опублікована в березні 1992
@uk
مقالة علمية (نشرت في 5-3-1992)
@ar
name
A chloride channel widely expressed in epithelial and non-epithelial cells
@ast
A chloride channel widely expressed in epithelial and non-epithelial cells
@en
A chloride channel widely expressed in epithelial and non-epithelial cells
@nl
type
label
A chloride channel widely expressed in epithelial and non-epithelial cells
@ast
A chloride channel widely expressed in epithelial and non-epithelial cells
@en
A chloride channel widely expressed in epithelial and non-epithelial cells
@nl
prefLabel
A chloride channel widely expressed in epithelial and non-epithelial cells
@ast
A chloride channel widely expressed in epithelial and non-epithelial cells
@en
A chloride channel widely expressed in epithelial and non-epithelial cells
@nl
P2093
P3181
P356
P1433
P1476
A chloride channel widely expressed in epithelial and non-epithelial cells
@en
P2093
A. Thiemann
S. Gründer
T. J. Jentsch
P2888
P3181
P356
10.1038/356057A0
P407
P577
1992-03-05T00:00:00Z
P5875
P6179
1012327154