A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome
about
End stage renal disease in patients with Wilms tumor: results from the National Wilms Tumor Study Group and the United States Renal Data System.Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferationRequirement of WT1 for gonad and adrenal development: insights from transgenic animals.Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway.Dysplastic and polycystic kidneys: diagnosis, associations and management.Growth and death in the developing mammalian kidney: signals, receptors and conversations.Genetic causes of proteinuria and nephrotic syndrome: impact on podocyte pathobiology.The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.Clinical and molecular characterization of patients with heterozygous mutations in wilms tumor suppressor gene 1.Insights into the physiological role of WT1 from studies of genetically modified mice.A role for the Wilms' tumor protein WT1 in organ development.Wilms' tumour: connecting tumorigenesis and organ development in the kidney.The multiassembly problem: reconstructing multiple transcript isoforms from EST fragment mixtures.New insights into the function of the Wilms tumor suppressor gene WT1 in podocytes.WT1 in disease: shifting the epithelial-mesenchymal balance.PAX2 in human kidney malformations and disease.Wt1 in the kidney--a tale in mouse models.Ectopic notch activation in developing podocytes causes glomerulosclerosis.WT1 Alternative Splicing: Role of Its Isoforms in Neuroblastoma.vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain.In vitro Cre/loxP system in cells from developing gonads: investigation of the Sry promoter.Wnt-4 regulation by the Wilms' tumour suppressor gene, WT1.The human sex-determining gene SRY is a direct target of WT1.A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus.Variants in the Wilms' tumor gene are associated with focal segmental glomerulosclerosis in the African American population.Clinical and genetic findings of five patients with WT1-related disorders.
P2860
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P2860
A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome
description
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1999
@ast
im März 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/03/16)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/03/16)
@nl
наукова стаття, опублікована в березні 1999
@uk
name
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@ast
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@en
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@nl
type
label
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@ast
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@en
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@nl
prefLabel
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@ast
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@en
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@nl
P2093
P2860
P356
P1476
A zinc finger truncation of mu ...... lities of Denys-Drash syndrome
@en
P2093
A. J. Brookes
A. R. Clarke
C. E. Patek
D. J. Harrison
D. J. Porteous
J. P. Charlieu
K. Miyagawa
M. H. Little
P2860
P304
P356
10.1073/PNAS.96.6.2931
P407
P577
1999-03-16T00:00:00Z