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RNAa is conserved in mammalian cellsThe loss of NKX3.1 expression in testicular--and prostate--cancers is not caused by promoter hypermethylationp63 is a prostate basal cell marker and is required for prostate developmentSOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formationUbiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1Loss of NKX3.1 favors vascular endothelial growth factor-C expression in prostate cancerAndrogen regulation of the prostatic tumour suppressor NKX3.1 is mediated by its 3' untranslated regionLoss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesisStructural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factorNKX3.1 activates expression of insulin-like growth factor binding protein-3 to mediate insulin-like growth factor-I signaling and cell proliferationNkx3.1 and p27(KIP1) cooperate in proliferation inhibition and apoptosis induction in human androgen-independent prostate cancer cellsInteractions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomainMyocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain proteinPurification and identification of a novel complex which is involved in androgen receptor-dependent transcriptionA novel function of caspase-8 in the regulation of androgen-receptor-driven gene expressionInflammatory cytokines induce phosphorylation and ubiquitination of prostate suppressor protein NKX3.1Growth, regeneration, and tumorigenesis of the prostate activates the PSCA promoterNkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cellsExome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancerMolecular alterations in prostate cancer as diagnostic, prognostic, and therapeutic targetsNKX3.1 expression is lost in testicular germ cell tumorsA network biology approach to prostate cancerThe role of Bapx1 (Nkx3.2) in the development and evolution of the axial skeletonPCGEM1, a prostate-specific gene, is overexpressed in prostate cancerExpressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostateAdvances in genetics: widening our understanding of prostate cancerMouse Models in Prostate Cancer Translational Research: From Xenograft to PDXGenetically engineered mouse models of prostate cancerGenetic interaction between Tmprss2-ERG gene fusion and Nkx3.1-loss does not enhance prostate tumorigenesis in mouse modelsThe smooth muscle gamma-actin gene is androgen responsive in prostate epitheliaOverexpression of the homeobox gene HOXC8 in human prostate cancer correlates with loss of tumor differentiationConcurrent Down-Regulation of PTEN and NKX3.1 Expression in Iranian Patients with Prostate CancerIncreased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptorSonic hedgehog-patched Gli signaling in the developing rat prostate gland: lobe-specific suppression by neonatal estrogens reduces ductal growth and branchingSecreted frizzled related protein 1 is a paracrine modulator of epithelial branching morphogenesis, proliferation, and secretory gene expression in the prostateHaploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostateMouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual developmentConditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasiaThe smooth muscle gamma-actin gene promoter is a molecular target for the mouse bagpipe homologue, mNkx3-1, and serum response factorId4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN
P2860
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P2860
description
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
@ast
im April 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/04/15)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/04/15)
@nl
наукова стаття, опублікована у квітні 1999
@uk
مقالة علمية (نشرت في 15-4-1999)
@ar
name
Roles for Nkx3.1 in prostate development and cancer
@ast
Roles for Nkx3.1 in prostate development and cancer
@en
Roles for Nkx3.1 in prostate development and cancer
@nl
type
label
Roles for Nkx3.1 in prostate development and cancer
@ast
Roles for Nkx3.1 in prostate development and cancer
@en
Roles for Nkx3.1 in prostate development and cancer
@nl
prefLabel
Roles for Nkx3.1 in prostate development and cancer
@ast
Roles for Nkx3.1 in prostate development and cancer
@en
Roles for Nkx3.1 in prostate development and cancer
@nl
P2093
P2860
P3181
P356
P1433
P1476
Roles for Nkx3.1 in prostate development and cancer
@en
P2093
A A Donjacour
C Abate-Shen
C R Norton
P J Sciavolino
R Bhatia-Gaur
R D Cardiff
P2860
P304
P3181
P356
10.1101/GAD.13.8.966
P577
1999-04-01T00:00:00Z