Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
about
Cellular transport and membrane dynamics of the glycine receptorGephyrin, the enigmatic organizer at GABAergic synapsesCharacterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesisMechanistic studies of human molybdopterin synthase reaction and characterization of mutants identified in group B patients of molybdenum cofactor deficiencyA mutation in the gene for the neurotransmitter receptor-clustering protein gephyrin causes a novel form of molybdenum cofactor deficiencyThe gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapseCortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray dataDefects of the Glycinergic Synapse in Zebrafish.A MusD retrotransposon insertion in the mouse Slc6a5 gene causes alterations in neuromuscular junction maturation and behavioral phenotypesDeterminants of different deep and superficial CA1 pyramidal cell dynamics during sharp-wave ripples.Mapping Synaptic Input Fields of Neurons with Super-Resolution Imaging.Crystal structure of the gephyrin-related molybdenum cofactor biosynthesis protein MogA from Escherichia coliX-ray crystal structure of the trimeric N-terminal domain of gephyrinCrystal structure of the GABAA-receptor-associated protein, GABARAPStructure of hypothetical Mo-cofactor biosynthesis protein B (ST2315) fromSulfolobus tokodaiiDesign and synthesis of high-affinity dimeric inhibitors targeting the interactions between gephyrin and inhibitory neurotransmitter receptorsMolecular basis of the alternative recruitment of GABA(A) versus glycine receptors through gephyrinHydrophobic interactions mediate binding of the glycine receptor beta-subunit to gephyrinCollybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrinIsoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor, and mutation analysis in hyperekplexiaIdentification of a gephyrin-binding motif in the GDP/GTP exchange factor collybistinGABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1Functional significance of isoform diversification in the protocadherin gamma gene clusterExonic Sp1 sites are required for neural-specific expression of the glycine receptor beta subunit genePost-phosphorylation prolyl isomerisation of gephyrin represents a mechanism to modulate glycine receptors functionTrak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic miceAltered inhibitory synaptic transmission in superficial dorsal horn neurones in spastic and oscillator miceDistribution of transcripts for the brain-specific GDP/GTP exchange factor collybistin in the developing mouse brainPalmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapsesCyclin-dependent kinase 5 is involved in the phosphorylation of gephyrin and clustering of GABAA receptors at inhibitory synapses of hippocampal neuronsBiochemical characterization of the high affinity binding between the glycine receptor and gephyrinSynArfGEF is a guanine nucleotide exchange factor for Arf6 and localizes preferentially at post-synaptic specializations of inhibitory synapsesActivated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeletonIdentification and characterisation of a Maf1/Macoco protein complex that interacts with GABAA receptors in neuronsMolecular basis of the γ-aminobutyric acid A receptor α3 subunit interaction with the clustering protein gephyrinTwo distinct proteins are associated with tetrameric acetylcholinesterase on the cell surfaceSimultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathyThe role of collybistin in gephyrin clustering at inhibitory synapses: facts and open questions.Complex role of collybistin and gephyrin in GABAA receptor clustering.
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P2860
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
description
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 1998
@ast
im November 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/11/13)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/11/13)
@nl
наукова стаття, опублікована в листопаді 1998
@uk
name
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@ast
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@en
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@nl
type
label
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@ast
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@en
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@nl
prefLabel
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@ast
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@en
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@nl
P2093
P3181
P1433
P1476
Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
@en
P2093
H. Tintrup
J. R. Sanes
M. C. Nichol
P304
P3181
P356
10.1126/SCIENCE.282.5392.1321
P407
P577
1998-11-13T00:00:00Z