The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis
about
Molecular cloning of a novel human I-mfa domain-containing protein that differently regulates human T-cell leukemia virus type I and HIV-1 expressionHuman Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domainsMEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promotersDifferential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2Requirement of the mouse I-mfa gene for placental development and skeletal patterningTranscription factor gene AP-2 gamma essential for early murine developmentThe function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesisThe HAND1 basic helix-loop-helix transcription factor regulates trophoblast differentiation via multiple mechanismsHelix-loop-helix proteins: regulators of transcription in eucaryotic organismsEndocannabinoid signaling in female reproductionThe basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of functionThe bHLH Transcription Factor Hand Regulates the Expression of Genes Critical to Heart and Muscle Function in Drosophila melanogasterHypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolismThe basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimerPhosphorylation of the Twist1-family basic helix-loop-helix transcription factors is involved in pathological cardiac remodelingDifferentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/deltaFetal overgrowth in the Cdkn1c mouse model of Beckwith-Wiedemann syndromeTranscriptional repressor erf determines extraembryonic ectoderm differentiationNucleolar release of Hand1 acts as a molecular switch to determine cell fateBlimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placentaRetinoid X receptors are essential for early mouse development and placentogenesisSUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineagesMorphogenesis of the right ventricle requires myocardial expression of Gata4Hectd1 is required for development of the junctional zone of the placentaThe imprinted Phlda2 gene regulates extraembryonic energy storesThe mouse KRAB zinc-finger protein CHATO is required in embryonic-derived tissues to control yolk sac and placenta morphogenesisMammalian Llgl2 is necessary for proper branching morphogenesis during placental developmentMst1 and mst2 are essential regulators of trophoblast differentiation and placenta morphogenesisHypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation.Hand2 loss-of-function in Hand1-expressing cells reveals distinct roles in epicardial and coronary vessel developmentCsf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice.Cytokeratins 8 and 19 in the mouse placental developmentTranscriptional regulator BPTF/FAC1 is essential for trophoblast differentiation during early mouse developmentCardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expressionTranscription factor AP-2gamma regulates murine adenosine deaminase gene expression during placental developmentMitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic developmentBuilding the mammalian heart from two sources of myocardial cellsThe Drosophila Hand gene is required for remodeling of the developing adult heart and midgut during metamorphosisAutomated discovery of tissue-targeting enhancers and transcription factors from binding motif and gene function data.
P2860
Q22253171-84FCC593-3A0F-4DAC-B259-E2570F686C49Q24292196-DD667D10-4B70-40B3-AF5A-8CAFFCA0E3B7Q24309833-5675A297-4CA6-423E-BC81-8DC22B0FD9E8Q24309987-6F470AE8-6593-4442-BADE-B5F82A629866Q24533371-965403A8-4F49-4A4E-8246-3B9B8D87978DQ24537286-A51D72F4-47BA-4656-BF7E-CC38313875A8Q24537671-147C7FF7-C482-4359-88F0-91FCBE22B418Q24552806-19D930F9-55AD-4064-AEA3-118A9082246FQ24554347-496115D5-F747-474D-B44B-4E288D7FA57BQ24554353-6CDF17C4-BC07-4C29-A4DC-198AF14A2C97Q24599033-EB2053DC-AD9B-4366-8D70-E77AFB32A838Q24657772-2AA3E926-6063-4F69-A6D4-B5291DA64DE5Q27301427-F4F54F11-40F1-4217-AB3F-544C5C63D99CQ27316790-872542CA-FDFC-429A-8CC0-8065293186E6Q28216746-FA85E943-BD3B-400F-A50E-FF692EF48B85Q28477980-D2564CBE-2AB1-48B1-B3D1-E6F6838994E9Q28504818-3F1BFA1D-2631-46CB-897F-7B0F45A2F2D9Q28505485-B7EE5DD7-E716-43CA-A44F-89DA49705B34Q28505544-BF38C68C-63DC-4101-9F33-42FF8CBBD72BQ28506343-B936D3F6-CCEA-4FB9-8BD7-438968EBE967Q28506546-60CAC89C-D726-4E9F-9BCF-5A091E49CB35Q28506736-3A7C4D56-C126-486A-81B7-0888BA345A9DQ28508647-976CB756-6B91-48DF-8E9D-AA00C39F52A2Q28509654-CF60E313-F0B5-4013-ACD0-45C4A769EE6DQ28510837-3168355F-2064-44C3-9B2A-2C71927029D2Q28512597-D614C9E8-EE61-4997-953B-9F7260741B79Q28513148-9AD56241-DCF2-4AC1-B4B4-F58BD24CB20AQ28513494-99BD380E-CB6D-49E1-9BA8-0B75B332CF55Q28585805-55215238-F879-4282-B969-56D69BBFE283Q28585983-6F319276-0246-4265-BE4D-06D1F56B836CQ28586477-480E3AB9-E70B-4472-A4A8-682B149D3C78Q28590729-4A0F3BB9-1C23-44CF-A879-80F125711B84Q28591688-04263524-8F9D-4240-BF51-1E39429F630CQ28593043-2A2706BC-154F-40AB-8BAD-E5C5D50F3358Q28593182-1631FD22-9549-426E-8C63-62D3A43B7C2EQ28593373-BB266C2A-6C53-4150-A7A8-6DAF022DEB57Q28594513-BA64B60D-637C-4C20-87A6-4C2B69A71C28Q29618590-022CE077-0E74-4BA9-BDFD-5A74260A4A96Q30480817-506FB470-8BE0-4F86-BFE3-94B96EDB35FCQ30749750-A59C26D2-1134-4B5D-B683-4BD6926E3335
P2860
The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis
description
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 1998
@ast
im März 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/03/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/03/01)
@nl
наукова стаття, опублікована в березні 1998
@uk
name
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@ast
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@en
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@nl
type
label
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@ast
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@en
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@nl
prefLabel
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@ast
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@en
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@nl
P2860
P3181
P356
P1433
P1476
The Hand1 bHLH transcription f ...... tion and cardiac morphogenesis
@en
P2093
Anson-Cartwright L
P2860
P2888
P304
P3181
P356
10.1038/NG0398-271
P407
P577
1998-03-01T00:00:00Z