RNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factors
about
Notch Signaling in Pancreatic DevelopmentTranscription factor regulation of pancreatic organogenesis, differentiation and maturationThe nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesisEctopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice.Next-generation sequencing identifies the Danforth's short tail mouse mutation as a retrotransposon insertion affecting Ptf1a expression.A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.Dominant and context-specific control of endodermal organ allocation by Ptf1a.Genome-wide association study and meta-analysis identify ISL1 as genome-wide significant susceptibility gene for bladder exstrophy.A pancreatic exocrine-like cell regulatory circuit operating in the upper stomach of the sea urchin Strongylocentrotus purpuratus larva.Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.Neurogenin3 cooperates with Foxa2 to autoactivate its own expression.Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility.Lineage determinants in early endocrine development.Gene regulatory networks governing pancreas development.Transcriptional control of mammalian pancreas organogenesis.Three-dimensional pancreas organogenesis models.Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.Nr5a2 heterozygosity sensitises to, and cooperates with, inflammation in KRas(G12V)-driven pancreatic tumourigenesis.Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment.New Neuronal Subtypes With a "Pre-Pancreatic" Signature in the Sea Urchin
P2860
Q26771258-5F14A81A-B269-4701-B986-9E65D55A0F3DQ28083955-F51D30C8-FF69-479B-8651-86E95F4CFA51Q28511736-495BDCDE-7366-418E-A39D-B80D6DBBB7F4Q31111669-4871580F-8661-4809-892A-6014ECEFF0E8Q34597913-E77F2D09-41F6-437A-844C-53DBD6000166Q34597925-99762956-4310-4837-B74D-8780E7B30987Q34999290-C62F3DBC-AAC8-43EA-89EB-160265D5B02AQ35170776-2AAB1B50-0B6D-4CD9-A378-3215340836C7Q36031403-DC27B268-AD36-4329-94E3-A800A39ED821Q36635346-FC8A904A-E485-409B-996E-BDAAD81025FCQ36796789-15BBC078-0EFA-4F9C-8199-354B8DD4F8F8Q37122854-EF1D382F-5630-4CC6-B592-A30C930D7342Q38021286-83BA2078-B0C6-49F5-BC44-BACFBEF50747Q38099904-331F77FC-36B7-4E99-BE91-2E44C2EB05F6Q38162099-18CAE67E-CDE2-49C2-9832-E66DD240362CQ38822489-04BAD143-3444-455A-80CF-8B0AD9608D7CQ42269245-2624E859-33EF-4D21-A3AA-D5DA697AD5E0Q51061806-60C76A34-0045-4E5C-AFC8-FA0CF7321F91Q55516479-DC7CC134-4F2C-425A-BE8C-20625CB00CE9Q59132163-F19E21B8-078D-4E3D-B345-11BEB2996A91
P2860
RNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factors
description
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im März 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/03/01)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/03/01)
@nl
наукова стаття, опублікована в березні 2012
@uk
مقالة علمية (نشرت في مارس 2012)
@ar
name
RNA profiling and chromatin im ...... of other transcription factors
@ast
RNA profiling and chromatin im ...... of other transcription factors
@en
RNA profiling and chromatin im ...... of other transcription factors
@nl
type
label
RNA profiling and chromatin im ...... of other transcription factors
@ast
RNA profiling and chromatin im ...... of other transcription factors
@en
RNA profiling and chromatin im ...... of other transcription factors
@nl
prefLabel
RNA profiling and chromatin im ...... of other transcription factors
@ast
RNA profiling and chromatin im ...... of other transcription factors
@en
RNA profiling and chromatin im ...... of other transcription factors
@nl
P2093
P2860
P3181
P356
P1476
RNA profiling and chromatin im ...... of other transcription factors
@en
P2093
Anne Grapin-Botton
Emilie Gésina
Nancy Thompson
Peter Scheinert
Philipp Bucher
P2860
P304
P3181
P356
10.1128/MCB.06318-11
P407
P577
2012-03-01T00:00:00Z