The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development
about
The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signalingEye morphogenesis and patterning of the optic vesicleEstablishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedbackStem Cell Therapy for Treatment of Ocular DisordersHedgehog Signaling in Pancreatic Fibrosis and CancerHoloprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humansThe mode of Hedgehog binding to Ihog homologues is not conserved across different phylaHedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active SiteGas1 extends the range of Hedgehog action by facilitating its signalingMechanisms that underlie co-variation of the brain and faceDistinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathwaysGrowth Arrest Specific-1 (GAS1) Is a C/EBP Target Gene That Functions in Ovulation and Corpus Luteum Formation in MicePersistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity.A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development.Using mechanistic Bayesian networks to identify downstream targets of the sonic hedgehog pathway.Genetic and biochemical definition of the Hedgehog receptor.Ethanol itself is a holoprosencephaly-inducing teratogen.The molecular genetics of holoprosencephaly.A primary cilia-dependent etiology for midline facial disorders.Hedgehog signaling in the normal and neoplastic mammary gland.Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube.Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicleTargeting Hedgehog--a cancer stem cell pathwayBoc modifies the spectrum of holoprosencephaly in the absence of Gas1 functionDynamic patterning at the pylorus: formation of an epithelial intestine-stomach boundary in late fetal life.Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shapeOverlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptorsCell signaling pathways in vertebrate lens regeneration.CDO, an Hh-coreceptor, mediates lung cancer cell proliferation and tumorigenicity through Hedgehog signalingGlypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signalingGas1 is a receptor for sonic hedgehog to repel enteric axons.Boc modifies the holoprosencephaly spectrum of Cdo mutant mice.Clinical implications of hedgehog signaling pathway inhibitorsSolution structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1.Hedgehog signaling in prostate epithelial-mesenchymal growth regulation.WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signalsOverweight in mice and enhanced adipogenesis in vitro are associated with lack of the hedgehog coreceptor boc.Key pathways regulated by HoxA9,10,11/HoxD9,10,11 during limb development.Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function
P2860
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P2860
The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development
description
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Mai 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/05/15)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/05/15)
@nl
наукова стаття, опублікована в травні 2007
@uk
مقالة علمية (نشرت في 15-5-2007)
@ar
name
The Hedgehog-binding proteins ...... aling during mouse development
@ast
The Hedgehog-binding proteins ...... aling during mouse development
@en
The Hedgehog-binding proteins ...... aling during mouse development
@nl
type
label
The Hedgehog-binding proteins ...... aling during mouse development
@ast
The Hedgehog-binding proteins ...... aling during mouse development
@en
The Hedgehog-binding proteins ...... aling during mouse development
@nl
prefLabel
The Hedgehog-binding proteins ...... aling during mouse development
@ast
The Hedgehog-binding proteins ...... aling during mouse development
@en
The Hedgehog-binding proteins ...... aling during mouse development
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
The Hedgehog-binding proteins ...... aling during mouse development
@en
P2093
Andrew P. McMahon
Benjamin L. Allen
Toyoaki Tenzen
P2860
P304
P3181
P356
10.1101/GAD.1543607
P577
2007-05-15T00:00:00Z