Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo.
about
Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctionsLipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT)Tumor Targeting and Drug Delivery by Anthrax ToxinThe Ins and Outs of Anthrax ToxinBacterial Toxins as Pathogen Weapons Against PhagocytesRoles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore FormationCrossing of the epithelial barriers by Bacillus anthracis: the Known and the UnknownAnthrax Toxins in Context of Bacillus anthracis Spores and Spore GerminationAnti-infective immunoadhesins from plants.Anthrax lethal and edema toxins in anthrax pathogenesisCytoskeleton as an emerging target of anthrax toxinsStudies in mice reveal a role for anthrax toxin receptors in matrix metalloproteinase function and extracellular matrix homeostasisCellular and physiological effects of anthrax exotoxin and its relevance to disease.Anthrax toxin receptor 2 functions in ECM homeostasis of the murine reproductive tract and promotes MMP activityThe Structure of Tumor Endothelial Marker 8 (TEM8) Extracellular Domain and Implications for Its Receptor Function for Recognizing Anthrax ToxinCathepsin B-mediated autophagy flux facilitates the anthrax toxin receptor 2-mediated delivery of anthrax lethal factor into the cytoplasmRegulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasisThe Disulfide Bond Cys255-Cys279 in the Immunoglobulin-Like Domain of Anthrax Toxin Receptor 2 Is Required for Membrane Insertion of Anthrax Protective Antigen PoreIdentification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay.Anthrax toxin uptake by primary immune cells as determined with a lethal factor-beta-lactamase fusion protein.Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptorsDisulfide bonds in the ectodomain of anthrax toxin receptor 2 are required for the receptor-bound protective-antigen pore to function.A femtomol range FRET biosensor reports exceedingly low levels of cell surface furin: implications for the processing of anthrax protective antigenAnthrax toxin triggers the activation of src-like kinases to mediate its own uptake.Cytolethal distending toxin B as a cell-killing component of tumor-targeted anthrax toxin fusion proteins.Direct interaction between anthrax toxin receptor 1 and the actin cytoskeletonCD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies.Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment.Targeting Bacillus anthracis toxicity with a genetically selected inhibitor of the PA/CMG2 protein-protein interactionCMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndromeKey tissue targets responsible for anthrax-toxin-induced lethality.Efficient targeting of head and neck squamous cell carcinoma by systemic administration of a dual uPA and MMP-activated engineered anthrax toxin.Tumor endothelium marker-8 based decoys exhibit superiority over capillary morphogenesis protein-2 based decoys as anthrax toxin inhibitors.Improving the anti-toxin abilities of the CMG2-Fc fusion protein with the aid of computational designComparative toxicity and efficacy of engineered anthrax lethal toxin variants with broad anti-tumor activitiesHeterodimeric integrin complexes containing beta1-integrin promote internalization and lethality of anthrax toxin.A receptor-based switch that regulates anthrax toxin pore formation.Anthrax toxin receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis.Hyaline fibromatosis syndrome with mutation c.1074delT of the CMG2 gene: a case reportA chimeric protein that functions as both an anthrax dual-target antitoxin and a trivalent vaccine.
P2860
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P2860
Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Capillary morphogenesis protei ...... ality of anthrax toxin in vivo
@nl
Capillary morphogenesis protei ...... lity of anthrax toxin in vivo.
@ast
Capillary morphogenesis protei ...... lity of anthrax toxin in vivo.
@en
type
label
Capillary morphogenesis protei ...... ality of anthrax toxin in vivo
@nl
Capillary morphogenesis protei ...... lity of anthrax toxin in vivo.
@ast
Capillary morphogenesis protei ...... lity of anthrax toxin in vivo.
@en
prefLabel
Capillary morphogenesis protei ...... ality of anthrax toxin in vivo
@nl
Capillary morphogenesis protei ...... lity of anthrax toxin in vivo.
@ast
Capillary morphogenesis protei ...... lity of anthrax toxin in vivo.
@en
P2093
P2860
P50
P921
P3181
P356
P1476
Capillary morphogenesis protei ...... lity of anthrax toxin in vivo.
@en
P2093
Devorah Crown
Haijing Hu
Hailun Wang
Sharmina Miller-Randolph
Thomas Morley
P2860
P304
12424-12429
P3181
P356
10.1073/PNAS.0905409106
P407
P577
2009-07-15T00:00:00Z