PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
about
Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson diseaseMUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkinUbiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysisPINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402Mitochondrial dysfunction in Parkinson's diseaseTransporting mitochondria in neuronsMetabolic, autophagic, and mitophagic activities in cancer initiation and progressionDegeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson's DiseaseUbiquitin modificationsCross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and DiseaseAlterations in Mitochondrial Quality Control in Alzheimer's DiseaseMitochondrial Quality Control and Muscle Mass MaintenanceThe Progress of Mitophagy and Related Pathogenic Mechanisms of the Neurodegenerative Diseases and TumorUnfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesMitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagyA Mechanistic Review of Mitophagy and Its Role in Protection against Alcoholic Liver DiseaseMitochondrial biogenesis and dynamics in the developing and diseased heartAutophagy-Related Deubiquitinating Enzymes Involved in Health and DiseaseAn experimental approach to study the function of mitochondria in cardiomyopathyMitochondrial dynamism and heart disease: changing shape and shaping changeRBR E3 ubiquitin ligases: new structures, new insights, new questionsTherapeutic targeting of autophagy: potential and concerns in treating cardiovascular diseaseMitophagy in hematopoietic stem cells: the case for explorationNew insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heartMending a broken heart: the role of mitophagy in cardioprotectionMitoconfusion: noncanonical functioning of dynamism factors in static mitochondria of the heartMorphological control of mitochondrial bioenergeticsMitochondrial quality control: decommissioning power plants in neurodegenerative diseasesPathologic and therapeutic implications for the cell biology of parkinRecent advances in mitochondrial researchFunctional implications of mitofusin 2-mediated mitochondrial-SR tetheringATM functions at the peroxisome to induce pexophagy in response to ROS.Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's diseaseStructure of the human Parkin ligase domain in an autoinhibited stateThe critical roles of mitophagy in cerebral ischemiaMitochondria in the Aging Muscles of Flies and Mice: New Perspectives for Old CharactersMitochondrial dynamics and viral infections: A close nexusMitochondrial fusion and fission proteins as novel therapeutic targets for treating cardiovascular diseaseNew therapeutics to modulate mitochondrial dynamics and mitophagy in cardiac diseasesParkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes
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P2860
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
description
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2013
@ast
im April 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/04/26)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/04/26)
@nl
наукова стаття, опублікована у квітні 2013
@uk
name
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@ast
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@en
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@nl
type
label
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@ast
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@en
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@nl
prefLabel
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@ast
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@en
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@nl
P2860
P921
P3181
P356
P1433
P1476
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
@en
P2093
Gerald W. Dorn
P2860
P304
P356
10.1126/SCIENCE.1231031
P407
P577
2013-04-26T00:00:00Z